Manuscripts Published

110 rows
# Number Title Authors Sitesort descending Year Journal Links
1 MS192 Defining Chronic Mucus Hypersecretion Using the CAT in the SPIROMICS Cohort. Stott-Miller, Marni ; Müllerová, Hana ; Miller, Bruce ; Tabberer, Maggie ; Baou, Céline El; Keeley, Tom ; Martinez, Fernando J.; Han, MeiLan ; Dransfield, Mark ; Hansel, Nadia N.; Cooper, Christopher B.; Woodruff, Prescott ; Ortega, Victor E.; Comellas, Alejandro P.; Iii, Robert Paine; Kanner, Richard E.; Anderson, Wayne ; Drummond, Bradley ; Kim, Victor ; Tal-Singer, Ruth ; Lazaar, Aili L. 2020 Int J Chron Obstruct Pulmon Dis 33116463
PMC7568676
2 MS156 Modeling residential indoor concentrations of PM , NO , NO , and secondhand smoke in the Subpopulations and Intermediate Outcome Measures in COPD (SPIROMICS) Air study. Zusman, Marina ; Gassett, Amanda J.; Kirwa, Kipruto ; Barr, Graham ; Cooper, Christopher B.; Han, Meilan K.; Kanner, Richard E.; Koehler, Kirsten ; Ortega, Victor E.; Rd, Robert Paine; Paulin, Laura ; Pirozzi, Cheryl ; Rule, Ana ; Hansel, Nadia N.; Kaufman, Joel D. 2021 Indoor Air 33037695
PMC8202242
3 MS206 Association Among Chronic Obstructive Pulmonary Disease Severity, Exacerbation Risk, and Anxiety and Depression Symptoms in the SPIROMICS Cohort. Weiss, Jacob R.; Serdenes, Ryan ; Madtha, Uchechukwu ; Zhao, Huaqing ; Kim, Victor ; Lopez-Pastrana, Jahaira ; Eakin, Michelle N.; O'Toole, Jacqueline ; Cooper, Christopher B.; Woodruff, Prescott ; Kanner, Richard E.; Krishnan, Jerry A.; Iyer, Anand S.; Couper, David ; Morrison, Mary F. Clinical Center: Pennsylvania (Temple University) 2022 J Acad Consult Liaison Psychiatry 35948252
4 MS085 Current smoking with or without chronic bronchitis is independently associated with goblet cell hyperplasia in healthy smokers and COPD subjects. Kim, Victor ; Jeong, Stephanie ; Zhao, Huaqing ; Kesimer, Mehmet ; Boucher, Richard C.; Wells, Michael ; Christenson, Stephanie A.; Han, Meilan K.; Dransfield, Mark ; Paine, Robert ; Cooper, Christopher B.; Barjaktarevic, Igor ; Bowler, Russell ; Curtis, Jeffrey L.; Kaner, Robert J.; O'Beirne, Sarah L.; O'Neal, Wanda K.; Rennard, Stephen I.; Martinez, Fernando J.; Woodruff, Prescott G. Clinical Center: Pennsylvania (Temple University) 2020 Sci Rep 33208859
PMC7674445
5 MS074 Clinically Significant and Comorbid Anxiety and Depression Symptoms Predict Severe Respiratory Exacerbations in Smokers: A Analysis of the COPDGene and SPIROMICS Cohorts. Iyer, Anand S.; Parekh, Trisha M.; O'Toole, Jacqueline ; Bhatt, Surya P.; Eakin, Michelle N.; Krishnan, Jerry A.; Yohannes, Abebaw M.; Woodruff, Prescott G.; Cooper, Christopher B.; Kanner, Richard E.; Hanania, Nicola A.; Dransfield, Mark T.; Regan, Elizabeth A.; Hoth, Karin F.; Kim, Victor Clinical Center: Pennsylvania (Temple University) 2022 Ann Am Thorac Soc 34343034
6 MS121 Association of Long-term Ambient Ozone Exposure With Respiratory Morbidity in Smokers. Paulin, Laura M.; Gassett, Amanda J.; Alexis, Neil E.; Kirwa, Kipruto ; Kanner, Richard E.; Peters, Stephen ; Krishnan, Jerry A.; Paine, Robert ; Dransfield, Mark ; Woodruff, Prescott G.; Cooper, Christopher B.; Barr, Graham ; Comellas, Alejandro P.; Pirozzi, Cheryl S.; Han, MeiLan ; Hoffman, Eric A.; Martinez, Fernando J.; Woo, Han ; Peng, Roger D.; Fawzy, Ashraf ; Putcha, Nirupama ; Breysse, Patrick N.; Kaufman, Joel D.; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2020 JAMA Intern Med 31816012
PMC6902160
7 MS178 Contribution of Individual and Neighborhood Factors to Racial Disparities in Respiratory Outcomes. Ejike, Chinedu O.; Woo, Han ; Galiatsatos, Panagis ; Paulin, Laura M.; Krishnan, Jerry A.; Cooper, Christopher B.; Couper, David J.; Kanner, Richard E.; Bowler, Russell P.; Hoffman, Eric A.; Comellas, Alejandro P.; Criner, Gerard J.; Barr, Graham ; Martinez, Fernando J.; Han, Meilan K.; Martinez, Carlos H.; Ortega, Victor E.; Parekh, Trisha M.; Christenson, Stephanie A.; Thakur, Neeta ; Baugh, Aaron ; Belz, Daniel C.; Raju, Sarath ; Gassett, Amanda J.; Kaufman, Joel D.; Putcha, Nirupama ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2021 Am J Respir Crit Care Med 33007162
PMC8048743
8 MS225 Ambient ozone effects on respiratory outcomes among smokers modified by neighborhood poverty: An analysis of SPIROMICS AIR. Belz, Daniel C.; Woo, Han ; Putcha, Nirupama ; Paulin, Laura M.; Koehler, Kirsten ; Fawzy, Ashraf ; Alexis, Neil E.; Barr, Graham ; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David ; Dransfield, Mark ; Gassett, Amanda J.; Han, MeiLan ; Hoffman, Eric A.; Kanner, Richard E.; Krishnan, Jerry A.; Martinez, Fernando J.; Paine, Robert ; Peng, Roger D.; Peters, Stephen ; Pirozzi, Cheryl S.; Woodruff, Prescott G.; Kaufman, Joel D.; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2022 Sci Total Environ 35318050
PMC9117415
9 MS087 Occupational Exposures and Computed Tomographic Imaging Characteristics in the SPIROMICS Cohort. Paulin, Laura M.; Smith, Benjamin M.; Koch, Abby ; Han, MeiLan ; Hoffman, Eric A.; Martinez, Carlos ; Ejike, Chinedu ; Blanc, Paul D.; Rous, Jennifer ; Barr, Graham ; Peters, Stephen P.; Paine, Robert ; Pirozzi, Cheryl ; Cooper, Christopher B.; Dransfield, Mark T.; Comellas, Alejandro P.; Kanner, Richard E.; Drummond, Brad ; Putcha, Nirupama ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2018 Ann Am Thorac Soc 30339479
PMC6322018
10 MS044 Anemia and Adverse Outcomes in a Chronic Obstructive Pulmonary Disease Population with a High Burden of Comorbidities. An Analysis from SPIROMICS. Putcha, Nirupama ; Fawzy, Ashraf ; Paul, Gabriel G.; Lambert, Allison A.; Psoter, Kevin J.; Sidhaye, Venkataramana K.; Woo, John ; Wells, Michael ; Labaki, Wassim W.; Doerschuk, Claire M.; Kanner, Richard E.; Han, Meilan K.; Martinez, Carlos ; Paulin, Laura M.; Martinez, Fernando J.; Wise, Robert A.; O'Neal, Wanda K.; Barr, Graham ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2018 Ann Am Thorac Soc 30726108
PMC6207135
11 MS011 Clinical Phenotypes of Atopy and Asthma in COPD: A Meta-analysis of SPIROMICS and COPDGene. Putcha, Nirupama ; Fawzy, Ashraf ; Matsui, Elizabeth C.; Liu, Mark C.; Bowler, Russ P.; Woodruff, Prescott G.; O'Neal, Wanda K.; Comellas, Alejandro P.; Han, Meilan K.; Dransfield, Mark T.; Wells, Michael ; Lugogo, Njira ; Gao, Li ; Talbot, Conover ; Hoffman, Eric A.; Cooper, Christopher B.; Paulin, Laura M.; Kanner, Richard E.; Criner, Gerard ; Ortega, Victor E.; Barr, Graham ; Krishnan, Jerry A.; Martinez, Fernando J.; Drummond, Bradley ; Wise, Robert A.; Diette, Gregory B.; Hersh, Craig P.; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2020 Chest 32450244
PMC7768932
12 MS089 Lower serum IgA is associated with COPD exacerbation risk in SPIROMICS. Putcha, Nirupama ; Paul, Gabriel G.; Azar, Antoine ; Wise, Robert A.; O'Neal, Wanda K.; Dransfield, Mark T.; Woodruff, Prescott G.; Curtis, Jeffrey L.; Comellas, Alejandro P.; Drummond, Bradley ; Lambert, Allison A.; Paulin, Laura M.; Fawzy, Ashraf ; Kanner, Richard E.; Paine, Robert ; Han, Meilan K.; Martinez, Fernando J.; Bowler, Russell P.; Barr, Graham ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2018 PLoS One 29649230
PMC5896903
13 MS271 Black carbon content in airway macrophages is associated with increased severe exacerbations and worse COPD morbidity in SPIROMICS Tejwani, Vickram ; Woo, Han ; Liu, Chen ; Tillery, Anna K.; Gassett, Amanda J.; Kanner, Richard E.; Hoffman, Eric A.; Martinez, Fernando J.; Woodruff, Prescott G.; Barr, Graham ; Fawzy, Ashraf ; Koehler, Kirsten ; Curtis, Jeffrey L.; Freeman, Christine M.; Cooper, Christopher B.; Comellas, Alejandro P.; Pirozzi, Cheryl ; Paine, Robert ; Tashkin, Donald ; Krishnan, Jerry A.; Sack, Coralynn ; Putcha, Nirupama ; Paulin, Laura M.; Zusman, Marina ; Kaufman, Joel D.; Alexis, Neil E.; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2022 Respir Res 36376879
PMC9664618
14 MS093 Association of thrombocytosis with COPD morbidity: the SPIROMICS and COPDGene cohorts. Fawzy, Ashraf ; Putcha, Nirupama ; Paulin, Laura M.; Aaron, Carrie P.; Labaki, Wassim W.; Han, Meilan K.; Wise, Robert A.; Kanner, Richard E.; Bowler, Russell P.; Barr, Graham ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2018 Respir Res 29373977
PMC5787242
15 MS010 A simplified score to quantify comorbidity in COPD. Putcha, Nirupama ; Puhan, Milo A.; Drummond, Bradley ; Han, Meilan K.; Regan, Elizabeth A.; Hanania, Nicola A.; Martinez, Carlos H.; Foreman, Marilyn ; Bhatt, Surya P.; Make, Barry ; Ramsdell, Joe ; DeMeo, Dawn L.; Barr, Graham ; Rennard, Stephen I.; Martinez, Fernando ; Silverman, Edwin K.; Crapo, James ; Wise, Robert A.; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2014 PLoS One 25514500
PMC4267736
16 MS125 The influence of social support on COPD outcomes mediated by depression. Turnier, Leonard ; Eakin, Michelle ; Woo, Han ; Dransfield, Mark ; Parekh, Trisha ; Krishnan, Jerry A.; Kanner, Richard ; Cooper, Christopher B.; Woodruff, Prescott G.; Wise, Robert ; Han, Meilan K.; Romero, Karina ; Paulin, Laura M.; Peters, Stephen ; Drummond, Brad ; Bleecker, Eugene R.; Bowler, Russell ; Comellas, Alejandro P.; Couper, David ; Paine, Robert ; Martinez, Fernando ; Barr, Graham ; Putcha, Nirupama ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2021 PLoS One 33730034
PMC7968645
17 MS112 Aspirin Use and Respiratory Morbidity in COPD: A Propensity Score-Matched Analysis in Subpopulations and Intermediate Outcome Measures in COPD Study. Fawzy, Ashraf ; Putcha, Nirupama ; Aaron, Carrie P.; Bowler, Russell P.; Comellas, Alejandro P.; Cooper, Christopher B.; Dransfield, Mark T.; Han, Meilan K.; Hoffman, Eric A.; Kanner, Richard E.; Krishnan, Jerry A.; Labaki, Wassim W.; Paine, Robert ; Paulin, Laura M.; Peters, Stephen P.; Wise, Robert ; Barr, Graham ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2019 Chest 30593776
PMC6414789
18 MS045 Cigarette smoke disrupts monolayer integrity by altering epithelial cell-cell adhesion and cortical tension. Nishida, Kristine ; Brune, Kieran A.; Putcha, Nirupama ; Mandke, Pooja ; O'Neal, Wanda K.; Shade, Danny ; Srivastava, Vasudha ; Wang, Menghan ; Lam, Hong ; An, Steven S.; Drummond, Bradley ; Hansel, Nadia N.; Robinson, Douglas N.; Sidhaye, Venkataramana K. Clinical Center: Baltimore (Johns Hopkins University) 2017 Am J Physiol Lung Cell Mol Physiol 28642260
PMC5625260
19 MS175 Disparities in access to food and chronic obstructive pulmonary disease (COPD)-related outcomes: a cross-sectional analysis. Moughames, Eric ; Woo, Han ; Galiatsatos, Panagis ; Romero-Rivero, Karina ; Raju, Sarath ; Tejwani, Vickram ; Hoffman, Eric A.; Comellas, Alejandro P.; Ortega, Victor E.; Parekh, Trisha ; Krishnan, Jerry A.; Drummond, Michael B.; Couper, David ; Buhr, Russell G.; Paine, Robert ; Kaufman, Joel D.; Paulin, Laura M.; Putcha, Nirupama ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2021 BMC Pulm Med 33906617
PMC8077917
20 MS013 Occupational exposures are associated with worse morbidity in patients with chronic obstructive pulmonary disease. Paulin, Laura M.; Diette, Gregory B.; Blanc, Paul D.; Putcha, Nirupama ; Eisner, Mark D.; Kanner, Richard E.; Belli, Andrew J.; Christenson, Stephanie ; Tashkin, Donald P.; Han, MeiLan ; Barr, Graham ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2015 Am J Respir Crit Care Med 25562375
PMC4384767
21 MS174 Comparative Impact of Depressive Symptoms and FEV% on Chronic Obstructive Pulmonary Disease. O'Toole, Jacqueline ; Woo, Han ; Putcha, Nirupama ; Cooper, Christopher B.; Woodruff, Prescott ; Kanner, Richard E.; Paine, Robert ; Bowler, Russell P.; Comellas, Alejandro ; Hoth, Karin F.; Krishnan, Jerry A.; Han, MeiLan ; Dransfield, Mark ; Iyer, Anand S.; Couper, David ; Peters, Stephen P.; Criner, Gerard ; Kim, Victor ; Barr, Graham ; Martinez, Fernando J.; Hansel, Nadia N.; Eakin, Michelle N. Clinical Center: Baltimore (Johns Hopkins University) 2022 Ann Am Thorac Soc 34410883
PMC8867359
22 MS037 Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort. Putcha, Nirupama ; Barr, Graham ; Han, Meilan K.; Woodruff, Prescott G.; Bleecker, Eugene R.; Kanner, Richard E.; Martinez, Fernando J.; Smith, Benjamin M.; Tashkin, Donald P.; Bowler, Russell P.; Eisner, Mark D.; Rennard, Stephen I.; Wise, Robert A.; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2016 Thorax 26962015
PMC5235992
23 MS173 The Association Between Neighborhood Socioeconomic Disadvantage and Chronic Obstructive Pulmonary Disease. Galiatsatos, Panagis ; Woo, Han ; Paulin, Laura M.; Kind, Amy ; Putcha, Nirupama ; Gassett, Amanda J.; Cooper, Christopher B.; Dransfield, Mark T.; Parekh, Trisha M.; Oates, Gabriela R.; Barr, Graham ; Comellas, Alejandro P.; Han, Meilan K.; Peters, Stephen P.; Krishnan, Jerry A.; Labaki, Wassim W.; McCormack, Meredith C.; Kaufman, Joel D.; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2020 Int J Chron Obstruct Pulmon Dis 32440110
PMC7211318
24 MS075 Subpopulations and Intermediate Outcomes in COPD (SPIROMICS) Air Pollution Study Design Hansel, Nadia N.; Paulin, Laura M.; Amanda, Gassett ; Roger, Peng ; Alexis, Neil E.; Fan, Vincent ; Bleecker, Eugene ; Bowler, Russell P.; Comellas, Alejandro P.; Dransfield, Mark T.; Han, Meilan K.; Kim, Victor ; Krishnan, Jerry A.; Pirozzi, Cheryl ; Cooper, Christopher B.; Martinez, Fernando J.; Woodruff, Prescott G.; Patrick, Breysse ; Barr, Graham ; Kaufman, Joel Clinical Center: Baltimore (Johns Hopkins University) 2017 BJM Open Respiratory Research
25 MS177 Polycythemia is Associated with Lower Incidence of Severe COPD Exacerbations in the SPIROMICS Study. Fawzy, Ashraf ; Woo, Han ; Balasubramanian, Aparna ; Barjaktarevic, Igor ; Barr, Graham ; Bowler, Russell P.; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David ; Criner, Gerard J.; Dransfield, Mark T.; Han, Meilan K.; Hoffman, Eric A.; Kanner, Richard E.; Krishnan, Jerry A.; Martinez, Fernando J.; McCormack, Meredith ; Iii, Robert Paine; Peters, Stephen ; Wise, Robert ; Woodruff, Prescott G.; Hansel, Nadia N.; Putcha, Nirupama Clinical Center: Baltimore (Johns Hopkins University) 2021 Chronic Obstr Pulm Dis 34197703
PMC8428597
26 MS178 Racial Segregation and Respiratory Outcomes among Urban Black Residents with and at Risk of Chronic Obstructive Pulmonary Disease. Woo, Han ; Brigham, Emily P.; Allbright, Kassandra ; Ejike, Chinedu ; Galiatsatos, Panagis ; Jones, Miranda R.; Oates, Gabriela R.; Krishnan, Jerry A.; Cooper, Christopher B.; Kanner, Richard E.; Bowler, Russell P.; Hoffman, Eric A.; Comellas, Alejandro P.; Criner, Gerard ; Barr, Graham ; Martinez, Fernando J.; Han, MeiLan ; Ortega, Victor E.; Parekh, Trisha M.; Christenson, Stephanie ; Belz, Daniel ; Raju, Sarath ; Gassett, Amanda ; Paulin, Laura M.; Putcha, Nirupama ; Kaufman, Joel D.; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2021 Am J Respir Crit Care Med 33971109
PMC8491265
27 MS198 The matrikine acetyl-proline-glycine-proline and clinical features of COPD: findings from SPIROMICS. Wells, Michael ; Xing, Dongqi ; Viera, Liliana ; Burkes, Robert M.; Wu, Yixin ; Bhatt, Surya P.; Dransfield, Mark T.; Couper, David J.; O'Neal, Wanda ; Hoffman, Eric A.; Gaggar, Amit ; Barjaktarevic, Igor ; Curtis, Jeffrey L.; Labaki, Wassim W.; Han, Mei Lan K.; Freeman, Christine M.; Putcha, Nirupama ; Schlange, Thomas ; Blalock, Edwin Clinical Center: Birmingham (University of Alabama at Birmingham) 2019 Respir Res 31718676
PMC6852714
28 MS122 Safety and Tolerability of Comprehensive Research Bronchoscopy in Chronic Obstructive Pulmonary Disease. Results from the SPIROMICS Bronchoscopy Substudy. Wells, Michael ; Arenberg, Douglas A.; Barjaktarevic, Igor ; Bhatt, Surya P.; Bowler, Russell P.; Christenson, Stephanie A.; Couper, David J.; Dransfield, Mark T.; Han, Meilan K.; Hoffman, Eric A.; Kaner, Robert J.; Kim, Victor ; Kleerup, Eric ; Martinez, Fernando J.; Moore, Wendy C.; O'Beirne, Sarah L.; Paine, Robert ; Putcha, Nirupama ; Raman, Sanjeev M.; Barr, Graham ; Rennard, Stephen I.; Woodruff, Prescott G.; Curtis, Jeffrey L. Clinical Center: Birmingham (University of Alabama at Birmingham) 2019 Ann Am Thorac Soc 30653926
PMC6441692
29 MS077 Elevated circulating MMP-9 is linked to increased COPD exacerbation risk in SPIROMICS and COPDGene. Wells, Michael ; Parker, Margaret M.; Oster, Robert A.; Bowler, Russ P.; Dransfield, Mark T.; Bhatt, Surya P.; Cho, Michael H.; Kim, Victor ; Curtis, Jeffrey L.; Martinez, Fernando J.; Paine, Robert ; O'Neal, Wanda ; Labaki, Wassim W.; Kaner, Robert J.; Barjaktarevic, Igor ; Han, Meilan K.; Silverman, Edwin K.; Crapo, James D.; Barr, Graham ; Woodruff, Prescott ; Castaldi, Peter J.; Gaggar, Amit Clinical Center: Birmingham (University of Alabama at Birmingham) 2018 JCI Insight 30429371
PMC6302944
30 MS142 Centrilobular emphysema and coronary artery calcification: mediation analysis in the SPIROMICS cohort. Bhatt, Surya P.; Nath, Hrudaya P.; Kim, Young-Il ; Ramachandran, Rekha ; Watts, Jubal R.; Terry, Nina L.J.; Sonavane, Sushil ; Deshmane, Swati P.; Woodruff, Prescott G.; Oelsner, Elizabeth C.; Bodduluri, Sandeep ; Han, Meilan K.; Labaki, Wassim W.; Wells, Michael ; Martinez, Fernando J.; Barr, Graham ; Dransfield, Mark T. Clinical Center: Birmingham (University of Alabama at Birmingham) 2018 Respir Res 30563576
PMC6299495
31 MS102 Marijuana Use Associations with Pulmonary Symptoms and Function in Tobacco Smokers Enrolled in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Morris, Madeline A.; Jacobson, Sean R.; Kinney, Gregory L.; Tashkin, Donald P.; Woodruff, Prescott G.; Hoffman, Eric A.; Kanner, Richard E.; Cooper, Christopher B.; Drummond, Brad ; Barr, Graham ; Oelsner, Elizabeth C.; Make, Barry J.; Han, Meilan K.; Hansel, Nadia N.; O'Neal, Wanda K.; Bowler, Russell P. Clinical Center: Denver (National Jewish Health) 2018 Chronic Obstr Pulm Dis 29629404
PMC5870739
32 MS205 Plasma Metabolomic Signatures of Chronic Obstructive Pulmonary Disease and the Impact of Genetic Variants on Phenotype-Driven Modules. Gillenwater, Lucas A.; Pratte, Katherine A.; Hobbs, Brian D.; Cho, Michael H.; Zhuang, Yonghua ; Halper-Stromberg, Eitan ; Cruickshank-Quinn, Charmion ; Reisdorph, Nichole ; Petrache, Irina ; Labaki, Wassim W.; O'Neal, Wanda K.; Ortega, Victor E.; Jones, Dean P.; Uppal, Karan ; Jacobson, Sean ; Michelotti, Gregory ; Wendt, Christine H.; Kechris, Katerina J.; Bowler, Russell P. Clinical Center: Denver (National Jewish Health) 2020 Netw Syst Med 33987620
PMC8109053
33 MS026 Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts. Keene, Jason D.; Jacobson, Sean ; Kechris, Katerina ; Kinney, Gregory L.; Foreman, Marilyn G.; Doerschuk, Claire M.; Make, Barry J.; Curtis, Jeffrey L.; Rennard, Stephen I.; Barr, Graham ; Bleecker, Eugene R.; Kanner, Richard E.; Kleerup, Eric C.; Hansel, Nadia N.; Woodruff, Prescott G.; Han, Meilan K.; Paine, Robert ; Martinez, Fernando J.; Bowler, Russell P.; O'Neal, Wanda K. Clinical Center: Denver (National Jewish Health) 2017 Am J Respir Crit Care Med 27579823
PMC5378424
34 MS205 Metabolomic Profiling Reveals Sex Specific Associations with Chronic Obstructive Pulmonary Disease and Emphysema. Gillenwater, Lucas A.; Kechris, Katerina J.; Pratte, Katherine A.; Reisdorph, Nichole ; Petrache, Irina ; Labaki, Wassim W.; O'Neal, Wanda ; Krishnan, Jerry A.; Ortega, Victor E.; DeMeo, Dawn L.; Bowler, Russell P. Clinical Center: Denver (National Jewish Health) 2021 Metabolites 33799786
PMC7999201
35 MS107 The value of blood cytokines and chemokines in assessing COPD. Bradford, Eric ; Jacobson, Sean ; Varasteh, Jason ; Comellas, Alejandro P.; Woodruff, Prescott ; O'Neal, Wanda ; DeMeo, Dawn L.; Li, Xingnan ; Kim, Victor ; Cho, Michael ; Castaldi, Peter J.; Hersh, Craig ; Silverman, Edwin K.; Crapo, James D.; Kechris, Katerina ; Bowler, Russell P. Clinical Center: Denver (National Jewish Health) 2017 Respir Res 29065892
PMC5655820
36 MS207 A Risk Prediction Model for Mortality Among Smokers in the COPDGene® Study. Strand, Matthew ; Austin, Erin ; Moll, Matthew ; Pratte, Katherine A.; Regan, Elizabeth A.; Hayden, Lystra P.; Bhatt, Surya P.; Boriek, Aladin M.; Casaburi, Richard ; Silverman, Edwin K.; Fortis, Spyridon ; Ruczinski, Ingo ; Koegler, Harald ; Rossiter, Harry B.; Occhipinti, Mariaelena ; Hanania, Nicola A.; Gebrekristos, Hirut T.; Lynch, David A.; Kunisaki, Ken M.; Young, Kendra A.; Sieren, Jessica C.; Ragland, Margaret ; Hokanson, John E.; Lutz, Sharon M.; Make, Barry J.; Kinney, Gregory L.; Cho, Michael H.; Pistolesi, Massimo ; DeMeo, Dawn L.; Sciurba, Frank C.; Comellas, Alejandro P.; Diaz, Alejandro A.; Barjaktarevic, Igor ; Bowler, Russell P.; Kanner, Richard E.; Peters, Stephen P.; Ortega, Victor E.; Dransfield, Mark T.; Crapo, James D. Clinical Center: Denver (National Jewish Health) 2020 Chronic Obstr Pulm Dis 32877963
PMC7883903
37 MS055 Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COPD. Pratte, Katherine A.; Curtis, Jeffrey L.; Kechris, Katerina ; Couper, David ; Cho, Michael H.; Silverman, Edwin K.; DeMeo, Dawn L.; Sciurba, Frank C.; Zhang, Yingze ; Ortega, Victor E.; O'Neal, Wanda K.; Gillenwater, Lucas A.; Lynch, David A.; Hoffman, Eric A.; Newell, John D.; Comellas, Alejandro P.; Castaldi, Peter J.; Miller, Bruce E.; Pouwels, Simon D.; Hacken, Nick H.T.Ten; Bischoff, Rainer ; Klont, Frank ; Woodruff, Prescott G.; Paine, Robert ; Barr, Graham ; Hoidal, John ; Doerschuk, Claire M.; Charbonnier, Jean-Paul ; Sung, Ruby ; Locantore, Nicholas ; Yonchuk, John G.; Jacobson, Sean ; Tal-Singer, Ruth ; Merrill, Debbie ; Bowler, Russell P. Clinical Center: Denver (National Jewish Health) 2021 Respir Res 33906653
PMC8076883
38 MS083 Electronic Cigarette Use in US Adults at Risk for or with COPD: Analysis from Two Observational Cohorts. Bowler, Russell P.; Hansel, Nadia N.; Jacobson, Sean ; Barr, Graham ; Make, Barry J.; Han, Meilan K.; O'Neal, Wanda K.; Oelsner, Elizabeth C.; Casaburi, Richard ; Barjaktarevic, Igor ; Cooper, Chris ; Foreman, Marilyn ; Wise, Robert A.; DeMeo, Dawn L.; Silverman, Edwin K.; Bailey, William ; Harrington, Kathleen F.; Woodruff, Prescott G.; Drummond, Bradley Clinical Center: Denver (National Jewish Health) 2017 J Gen Intern Med 28884423
PMC5698219
39 MS246 A Metabolomic Severity Score for Airflow Obstruction and Emphysema. Godbole, Suneeta ; Labaki, Wassim W.; Pratte, Katherine A.; Hill, Andrew ; Moll, Matthew ; Hastie, Annette T.; Peters, Stephen P.; Gregory, Andrew ; Ortega, Victor E.; Demeo, Dawn ; Cho, Michael H.; Bhatt, Surya P.; Wells, Michael ; Barjaktarevic, Igor ; Stringer, Kathleen A.; Comellas, Alejandro ; O'Neal, Wanda ; Kechris, Katerina ; Bowler, Russell P. Clinical Center: Denver (National Jewish Health) 2022 Metabolites 35629872
PMC9143560
40 MS203 Bronchoalveolar Lavage Fluid from COPD Patients Reveals More Compounds Associated with Disease than Matched Plasma. Halper-Stromberg, Eitan ; Gillenwater, Lucas ; Cruickshank-Quinn, Charmion ; O'Neal, Wanda Kay; Reisdorph, Nichole ; Petrache, Irina ; Zhuang, Yonghua ; Labaki, Wassim W.; Curtis, Jeffrey L.; Wells, James ; Rennard, Stephen ; Pratte, Katherine A.; Woodruff, Prescott ; Stringer, Kathleen A.; Kechris, Katerina ; Bowler, Russell P. Clinical Center: Denver (National Jewish Health) 2019 Metabolites 31349744
PMC6724137
41 MS259 Bronchodilator Responsiveness in Tobacco-Exposed Persons with or without COPD Fortis, Spyridon ; Quibrera, Pedro M.; Comellas, Alejandro P.; Bhatt, Surya P.; Tashkin, Donald P.; Hoffman, Eric A.; Criner, Gerard J.; Han, Meilan K.; Barr, Graham ; Arjomandi, Mehrdad ; Dransfield, Mark B.; Peters, Stephen P.; Dolezal, Brett A.; Kim, Victor ; Putcha, Nirupama ; Rennard, Stephen I.; Paine, Robert ; Kanner, Richard E.; Curtis, Jeffrey L.; Bowler, Russell P.; Martinez, Fernando J.; Hansel, Nadia N.; Krishnan, Jerry A.; Woodruff, Prescott G.; Barjaktarevic, Igor Z.; Couper, David ; Anderson, Wayne H.; Cooper, Christopher B. Clinical Center: Iowa (University of Iowa) 2022 Chest 36395858
42 MS191 Ratio of FEV/Slow Vital Capacity of < 0.7 Is Associated With Clinical, Functional, and Radiologic Features of Obstructive Lung Disease in Smokers With Preserved Lung Function. Fortis, Spyridon ; Comellas, Alejandro P.; Bhatt, Surya P.; Hoffman, Eric A.; Han, Meilan K.; Bhakta, Nirav R.; Paine, Robert ; Ronish, Bonnie ; Kanner, Richard E.; Dransfield, Mark ; Hoesterey, Daniel ; Buhr, Russell G.; Barr, Graham ; Dolezal, Brett ; Ortega, Victor E.; Drummond, Bradley ; Arjomandi, Mehrdad ; Kaner, Robert J.; Kim, Victor ; Curtis, Jeffrey L.; Bowler, Russell P.; Martinez, Fernando ; Labaki, Wassim W.; Cooper, Christopher B.; O'Neal, Wanda K.; Criner, Gerald ; Hansel, Nadia N.; Krishnan, Jerry A.; Woodruff, Prescott ; Couper, David ; Tashkin, Donald ; Barjaktarevic, Igor Clinical Center: Iowa (University of Iowa) 2021 Chest 33539837
PMC8295909
43 MS200 Latent traits of lung tissue patterns in former smokers derived by dual channel deep learning in computed tomography images. Li, Frank ; Choi, Jiwoong ; Zou, Chunrui ; Newell, John D.; Comellas, Alejandro P.; Lee, Chang Hyun; Ko, Hongseok ; Barr, Graham ; Bleecker, Eugene R.; Cooper, Christopher B.; Abtin, Fereidoun ; Barjaktarevic, Igor ; Couper, David ; Han, MeiLan ; Hansel, Nadia N.; Kanner, Richard E.; Paine, Robert ; Kazerooni, Ella A.; Martinez, Fernando J.; O'Neal, Wanda ; Rennard, Stephen I.; Smith, Benjamin M.; Woodruff, Prescott G.; Hoffman, Eric A.; Lin, Ching-Long Clinical Center: Iowa (University of Iowa) 2021 Sci Rep 33649381
PMC7921389
44 MS068 A controlled statistical study to assess measurement variability as a function of test object position and configuration for automated surveillance in a multicenter longitudinal COPD study (SPIROMICS). Guo, Junfeng ; Wang, Chao ; Chan, Kung-Sik ; Jin, Dakai ; Saha, Punam K.; Sieren, Jered P.; Barr, R G.; Han, Meilan K.; Kazerooni, Ella ; Cooper, Christopher B.; Couper, David ; Newell, John D.; Hoffman, Eric A. Clinical Center: Iowa (University of Iowa) 2016 Med Phys 27147369
PMC4851622
45 MS200 Longitudinal Imaging-Based Clusters in Former Smokers of the COPD Cohort Associate with Clinical Characteristics: The SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Zou, Chunrui ; Li, Frank ; Choi, Jiwoong ; Haghighi, Babak ; Choi, Sanghun ; Rajaraman, Prathish K.; Comellas, Alejandro P.; Newell, John D.; Lee, Chang Hyun; Barr, Graham ; Bleecker, Eugene ; Cooper, Christopher B.; Couper, David ; Han, MeiLan ; Hansel, Nadia N.; Kanner, Richard E.; Kazerooni, Ella A.; Kleerup, Eric C.; Martinez, Fernando J.; O'Neal, Wanda ; Paine, Robert ; Rennard, Stephen I.; Smith, Benjamin M.; Woodruff, Prescott G.; Hoffman, Eirc A.; Lin, Ching-Long Clinical Center: Iowa (University of Iowa) 2021 Int J Chron Obstruct Pulmon Dis 34103907
PMC8178702
46 MS200 Imaging-based clusters in former smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and intermediate outcome measures in COPD study (SPIROMICS). Haghighi, Babak ; Choi, Sanghun ; Choi, Jiwoong ; Hoffman, Eric A.; Comellas, Alejandro P.; Newell, John D.; Lee, Chang Hyun; Barr, Graham ; Bleecker, Eugene ; Cooper, Christopher B.; Couper, David ; Han, Mei Lan; Hansel, Nadia N.; Kanner, Richard E.; Kazerooni, Ella A.; Kleerup, Eric A.C.; Martinez, Fernando J.; O'Neal, Wanda ; Paine, Robert ; Rennard, Stephen I.; Smith, Benjamin M.; Woodruff, Prescott G.; Lin, Ching-Long Clinical Center: Iowa (University of Iowa) 2019 Respir Res 31307479
PMC6631615
47 MS006 Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis. Barjaktarevic, Igor Z.; Buhr, Russell G.; Wang, Xiaoyan ; Hu, Scott ; Couper, David ; Anderson, Wayne ; Kanner, Richard E.; Iii, Robert Paine; Bhatt, Surya P.; Bhakta, Nirav R.; Arjomandi, Mehrdad ; Kaner, Robert J.; Pirozzi, Cheryl S.; Curtis, Jeffrey L.; O'Neal, Wanda K.; Woodruff, Prescott G.; Han, Meilan K.; Martinez, Fernando J.; Hansel, Nadia ; Wells, James Michael; Ortega, Victor E.; Hoffman, Eric A.; Doerschuk, Claire M.; Kim, Victor ; Dransfield, Mark T.; Drummond, Bradley ; Bowler, Russell ; Criner, Gerard ; Christenson, Stephanie A.; Ronish, Bonnie ; Peters, Stephen P.; Krishnan, Jerry A.; Tashkin, Donald P.; Cooper, Christopher B. Clinical Center: Los Angeles (University of California at Los Angeles) 2019 Int J Chron Obstruct Pulmon Dis 31908441
PMC6930016
48 MS038 Novel Respiratory Disability Score Predicts COPD Exacerbations and Mortality in the SPIROMICS Cohort. Cooper, Christopher B.; Paine, Robert ; Curtis, Jeffrey L.; Kanner, Richard E.; Martinez, Carlos H.; Meldrum, Catherine A.; Bowler, Russell ; O'Neal, Wanda ; Hoffman, Eric A.; Couper, David ; Quibrera, Miguel ; Criner, Gerald ; Dransfield, Mark T.; Han, Meilan K.; Hansel, Nadia N.; Krishnan, Jerry A.; Lazarus, Stephen C.; Peters, Stephen P.; Barr, Graham ; Martinez, Fernando J.; Woodruff, Prescott G. Clinical Center: Los Angeles (University of California at Los Angeles) 2020 Int J Chron Obstruct Pulmon Dis 32821092
PMC7417644
49 MS012 Sleep disruption as a predictor of quality of life among patients in the subpopulations and intermediate outcome measures in COPD study (SPIROMICS). Zeidler, Michelle R.; Martin, Jennifer L.; Kleerup, Eric C.; Schneider, Hartmut ; Mitchell, Michael N.; Hansel, Nadia N.; Sundar, Krishna ; Schotland, Helena ; Basner, Robert C.; Wells, Michael ; Krishnan, Jerry A.; Criner, Gerard J.; Cristenson, Stephanie ; Krachman, Samuel ; Badr, Safwan Clinical Center: Los Angeles (University of California at Los Angeles) 2018 Sleep 29534240
PMC5946919
50 MS168 Significance of FEV/FEV in Recognition of Early Airway Disease in Smokers at Risk of Development of COPD: Analysis of the SPIROMICS Cohort. Yee, Nathan ; Markovic, Daniela ; Buhr, Russell G.; Fortis, Spyridon ; Arjomandi, Mehrdad ; Couper, David ; Anderson, Wayne H.; Paine, Robert ; Woodruff, Prescott G.; Han, Meilan K.; Martinez, Fernando J.; Barr, Graham ; Wells, James M.; Ortega, Victor E.; Hoffman, Eric A.; Kim, Victor ; Drummond, Bradley ; Bowler, Russell P.; Curtis, Jeffrey L.; Cooper, Christopher B.; Tashkin, Donald P.; Barjaktarevic, Igor Z. Clinical Center: Los Angeles (University of California at Los Angeles) 2022 Chest 34767825
PMC9005864
51 MS163 Reversible Airflow Obstruction Predicts Future Chronic Obstructive Pulmonary Disease Development in the SPIROMICS Cohort: An Observational Cohort Study. Buhr, Russell G.; Barjaktarevic, Igor Z.; Quibrera, Miguel ; Bateman, Lori A.; Bleecker, Eugene R.; Couper, David J.; Curtis, Jeffrey L.; Dolezal, Brett A.; Han, Meilan K.; Hansel, Nadia N.; Krishnan, Jerry A.; Martinez, Fernando J.; McKleroy, William ; Paine, Robert ; Rennard, Stephen I.; Tashkin, Donald P.; Woodruff, Prescott G.; Kanner, Richard E.; Cooper, Christopher B. Clinical Center: Los Angeles (University of California at Los Angeles) 2022 Am J Respir Crit Care Med 35549640
52 MS263 Effect of marijuana smoking on lung function change in older ever tobacco smokers. Barjaktarevic, Igor ; Cooper, Christopher B.; Shing, Tracie ; Buhr, Russell G.; Hoffman, Eric A.; Woodruff, Prescott G.; Drummond, Bradley ; Kanner, Richard E.; Han, Meilan K.; Hansel, Nadia N.; Bowler, Russell P.; Kinney, Gregory L.; Jacobson, Sean ; Morris, Madeline A.; Martinez, Fernando J.; Ohar, Jill ; Couper, David ; Tashkin, Donald P. Clinical Center: Los Angeles (University of California at Los Angeles) 2022 Eur Respir J 36137583
53 MS239 Clinical implications of low absolute blood eosinophil count in the SPIROMICS COPD cohort LeMaster, Blake ; Quibrera, Miguel ; Couper, David ; Tashkin, Donald P.; Bleecker, Eugene R.; Doerschuk, Claire M.; Ortega, Victor E.; Cooper, Christopher ; Han, Meilan K.; Woodruff, Prescott G.; O'Neal, Wanda K.; Anderson, Wayne H.; Alexis, Neil E.; Bowler, Russell P.; Barr, Graham ; Kaner, Robert J.; Dransfield, Mark T.; Paine, Robert ; Kim, Victor ; Curtis, Jeffrey L.; Martinez, Fernando J.; Hastie, Annette T.; Barjaktarevic, Igor Clinical Center: Los Angeles (University of California at Los Angeles) 2022 Chest 36343688
54 MS080 Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort. Martinez, Carlos H.; Li, Sara X.; Hirzel, Andrew J.; Stolberg, Valerie R.; Alexis, Neil E.; Barr, Graham ; Bleecker, Eugene R.; Carretta, Elizabeth E.; Christenson, Stephanie A.; Cooper, Christopher B.; Couper, David J.; Doerschuk, Claire M.; Han, Meilan K.; Hansel, Nadia N.; Hastie, Annette T.; Hoffman, Eric A.; Kaner, Robert J.; Martinez, Fernando J.; Meyers, Deborah A.; O'Neal, Wanda K.; Paine, Robert ; Putcha, Nirupama ; Rennard, Stephen I.; Woodruff, Prescott G.; Zeidler, Michelle ; Curtis, Jeffrey L.; Freeman, Christine M. Clinical Center: Michigan (University of Michigan) 2018 J Allergy Clin Immunol 28916185
PMC5758424
55 MS022 Association between Emphysema and Chronic Obstructive Pulmonary Disease Outcomes in the COPDGene and SPIROMICS Cohorts: A Post Hoc Analysis of Two Clinical Trials. Han, Meilan K.; Tayob, Nabihah ; Murray, Susan ; Woodruff, Prescott G.; Curtis, Jeffrey L.; Kim, Victor ; Criner, Gerard ; Galbán, Craig J.; Ross, Brian D.; Hoffman, Eric A.; Lynch, David A.; Kazerooni, Ella ; Martinez, Fernando J. Clinical Center: Michigan (University of Michigan) 2018 Am J Respir Crit Care Med 29485901
PMC6058986
56 MS017 Design of a multi-center immunophenotyping analysis of peripheral blood, sputum and bronchoalveolar lavage fluid in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Freeman, Christine M.; Crudgington, Sean ; Stolberg, Valerie R.; Brown, Jeanette P.; Sonstein, Joanne ; Alexis, Neil E.; Doerschuk, Claire M.; Basta, Patricia V.; Carretta, Elizabeth E.; Couper, David J.; Hastie, Annette T.; Kaner, Robert J.; O'Neal, Wanda K.; Paine, Robert ; Rennard, Stephen I.; Shimbo, Daichi ; Woodruff, Prescott G.; Zeidler, Michelle ; Curtis, Jeffrey L. Clinical Center: Michigan (University of Michigan) 2015 J Transl Med 25622723
PMC4314767
57 MS078 Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort. Martinez, Carlos H.; Murray, Susan ; Barr, Graham ; Bleecker, Eugene ; Bowler, Russell P.; Christenson, Stephanie A.; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David ; Criner, Gerard J.; Curtis, Jeffrey L.; Dransfield, Mark T.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Kleerup, Eric ; Krishnan, Jerry A.; Lazarus, Stephen C.; Leidy, Nancy K.; O'Neal, Wanda ; Martinez, Fernando J.; Paine, Robert ; Rennard, Stephen I.; Tashkin, Donald P.; Woodruff, Prescott G.; Han, Meilan K. Clinical Center: Michigan (University of Michigan) 2017 Ann Am Thorac Soc 28459622
PMC5427740
58 MS162 Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort. Opron, Kristopher ; Begley, Lesa A.; Erb-Downward, John R.; Freeman, Christine ; Madapoosi, Siddharth ; Alexis, Neil E.; Barjaktarevic, Igor ; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Christenson, Stephanie A.; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David J.; Doerschuk, Claire M.; Dransfield, Mark T.; Han, Meilan K.; Hansel, Nadia N.; Hastie, Annette T.; Hoffman, Eric A.; Kaner, Robert J.; Krishnan, Jerry ; O'Neal, Wanda K.; Ortega, Victor E.; Paine, Robert ; Peters, Stephen P.; Wells, Michael ; Woodruff, Prescott G.; Martinez, Fernando J.; Curtis, Jeffrey L.; Huffnagle, Gary B.; Huang, Yvonne J. Clinical Center: Michigan (University of Michigan) 2021 NPJ Biofilms Microbiomes 33547327
PMC7865064
59 MS036 Age-Related Differences in Health-Related Quality of Life in COPD: An Analysis of the COPDGene and SPIROMICS Cohorts. Martinez, Carlos H.; Diaz, Alejandro A.; Parulekar, Amit D.; Rennard, Stephen I.; Kanner, Richard E.; Hansel, Nadia N.; Couper, David ; Holm, Kristen E.; Hoth, Karin F.; Curtis, Jeffrey L.; Martinez, Fernando J.; Hanania, Nicola A.; Regan, Elizabeth A.; Paine, Robert ; Cigolle, Christine T.; Han, Meilan K. Clinical Center: Michigan (University of Michigan) 2016 Chest 26836895
PMC4944781
60 MS051 Age and Small Airway Imaging Abnormalities in Subjects with and without Airflow Obstruction in SPIROMICS. Martinez, Carlos H.; Diaz, Alejandro A.; Meldrum, Catherine ; Curtis, Jeffrey L.; Cooper, Christopher B.; Pirozzi, Cheryl ; Kanner, Richard E.; Paine, Robert ; Woodruff, Prescott G.; Bleecker, Eugene R.; Hansel, Nadia N.; Barr, Graham ; Marchetti, Nathaniel ; Criner, Gerard J.; Kazerooni, Ella A.; Hoffman, Eric A.; Ross, Brian D.; Galbán, Craig J.; Cigolle, Christine T.; Martinez, Fernando J.; Han, Meilan K. Clinical Center: Michigan (University of Michigan) 2017 Am J Respir Crit Care Med 27564413
PMC5378423
61 MS145 Serum amino acid concentrations and clinical outcomes in smokers: SPIROMICS metabolomics study. Labaki, Wassim W.; Gu, Tian ; Murray, Susan ; Curtis, Jeffrey L.; Yeomans, Larisa ; Bowler, Russell P.; Barr, Graham ; Comellas, Alejandro P.; Hansel, Nadia N.; Cooper, Christopher B.; Barjaktarevic, Igor ; Kanner, Richard E.; Paine, Robert ; McDonald, Merry-Lynn N.; Krishnan, Jerry A.; Peters, Stephen P.; Woodruff, Prescott G.; O'Neal, Wanda K.; Diao, Wenqi ; He, Bei ; Martinez, Fernando J.; Standiford, Theodore J.; Stringer, Kathleen A.; Han, Meilan K. Clinical Center: Michigan (University of Michigan) 2019 Sci Rep 31388056
PMC6684630
62 MS097 Correcting Nonpathological Variation in Longitudinal Parametric Response Maps of CT Scans in COPD Subjects: SPIROMICS. Fernández-Baldera, Antonio ; Hatt, Charles R.; Murray, Susan ; Hoffman, Eric A.; Kazerooni, Ella A.; Martinez, Fernando J.; Han, Meilan K.; Galbán, Craig J. Clinical Center: Michigan (University of Michigan) 2017 Tomography 29457137
PMC5812694
63 MS019 Parametric response mapping monitors temporal changes on lung CT scans in the subpopulations and intermediate outcome measures in COPD Study (SPIROMICS). Boes, Jennifer L.; Hoff, Benjamin A.; Bule, Maria ; Johnson, Timothy D.; Rehemtulla, Alnawaz ; Chamberlain, Ryan ; Hoffman, Eric A.; Kazerooni, Ella A.; Martinez, Fernando J.; Han, Meilan K.; Ross, Brian D.; Galbán, Craig J. Clinical Center: Michigan (University of Michigan) 2015 Acad Radiol 25442794
PMC4289437
64 MS095 NT-proBNP in stable COPD and future exacerbation risk: Analysis of the SPIROMICS cohort. Labaki, Wassim W.; Xia, Meng ; Murray, Susan ; Curtis, Jeffrey L.; Barr, Graham ; Bhatt, Surya P.; Bleecker, Eugene R.; Hansel, Nadia N.; Cooper, Christopher B.; Dransfield, Mark T.; Wells, Michael ; Hoffman, Eric A.; Kanner, Richard E.; Paine, Robert ; Ortega, Victor E.; Peters, Stephen P.; Krishnan, Jerry A.; Bowler, Russell P.; Couper, David J.; Woodruff, Prescott G.; Martinez, Fernando J.; Martinez, Carlos H.; Han, Meilan K. Clinical Center: Michigan (University of Michigan) 2018 Respir Med 29957287
PMC6084793
65 MS209 Lung Microbiota and Metabolites Collectively Associate with Clinical Outcomes in Milder Stage Chronic Obstructive Pulmonary Disease. Madapoosi, Siddharth S.; Cruickshank-Quinn, Charmion ; Opron, Kristopher ; Erb-Downward, John R.; Begley, Lesa A.; Li, Gen ; Barjaktarevic, Igor ; Barr, Graham ; Comellas, Alejandro P.; Couper, David J.; Cooper, Christopher B.; Freeman, Christine M.; Han, Meilan K.; Kaner, Robert J.; Labaki, Wassim ; Martinez, Fernando J.; Ortega, Victor E.; Peters, Stephen P.; Paine, Robert ; Woodruff, Prescott ; Curtis, Jeffrey L.; Huffnagle, Gary B.; Stringer, Kathleen A.; Bowler, Russell P.; Esther, Charles R.; Reisdorph, Nichole ; Huang, Yvonne J. Clinical Center: Michigan (University of Michigan) 2022 Am J Respir Crit Care Med 35536732
66 MS034 Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. Han, Meilan K.; Quibrera, Pedro M.; Carretta, Elizabeth E.; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Cooper, Christopher B.; Comellas, Alejandro ; Couper, David J.; Curtis, Jeffrey L.; Criner, Gerard ; Dransfield, Mark T.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Krishnan, Jerry A.; Martinez, Carlos H.; Pirozzi, Cheryl B.; O'Neal, Wanda K.; Rennard, Stephen ; Tashkin, Donald P.; Wedzicha, Jadwiga A.; Woodruff, Prescott ; Paine, Robert ; Martinez, Fernando J. Clinical Center: Michigan (University of Michigan) 2017 Lancet Respir Med 28668356
PMC5558856
67 MS053 Human airway branch variation and chronic obstructive pulmonary disease. Smith, Benjamin M.; Traboulsi, Hussein ; Austin, John H.M.; Manichaikul, Ani ; Hoffman, Eric A.; Bleecker, Eugene R.; Cardoso, Wellington V.; Cooper, Christopher ; Couper, David J.; Dashnaw, Stephen M.; Guo, Jia ; Han, Meilan K.; Hansel, Nadia N.; Hughes, Emlyn W.; Jacobs, David R.; Kanner, Richard E.; Kaufman, Joel D.; Kleerup, Eric ; Lin, Ching-Long ; Liu, Kiang ; Cascio, Christian M.Lo; Martinez, Fernando J.; Nguyen, Jennifer N.; Prince, Martin R.; Rennard, Stephen ; Rich, Stephen S.; Simon, Leora ; Sun, Yanping ; Watson, Karol E.; Woodruff, Prescott G.; Baglole, Carolyn J.; Barr, Graham Clinical Center: New York (Columbia University) 2018 Proc Natl Acad Sci U S A 29339516
PMC5798356
68 MS119 A Genetic Risk Score Associated with Chronic Obstructive Pulmonary Disease Susceptibility and Lung Structure on Computed Tomography. Oelsner, Elizabeth C.; Ortega, Victor E.; Smith, Benjamin M.; Nguyen, Jennifer N.; Manichaikul, Ani W.; Hoffman, Eric A.; Guo, Xiuqing ; Taylor, Kent D.; Woodruff, Prescott G.; Couper, David J.; Hansel, Nadia N.; Martinez, Fernando J.; Paine, Robert ; Han, Meilan K.; Cooper, Christopher ; Dransfield, Mark T.; Criner, Gerard ; Krishnan, Jerry A.; Bowler, Russell ; Bleecker, Eugene R.; Peters, Stephen ; Rich, Stephen S.; Meyers, Deborah A.; Rotter, Jerome I.; Barr, Graham Clinical Center: New York (Columbia University) 2019 Am J Respir Crit Care Med 30925230
PMC6775892
69 MS018 Comparison of spatially matched airways reveals thinner airway walls in COPD. The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study and the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). Smith, Benjamin M.; Hoffman, Eric A.; Rabinowitz, Dan ; Bleecker, Eugene ; Christenson, Stephanie ; Couper, David ; Donohue, Kathleen M.; Han, Meilan K.; Hansel, Nadia N.; Kanner, Richard E.; Kleerup, Eric ; Rennard, Stephen ; Barr, Graham Clinical Center: New York (Columbia University) 2014 Thorax 24928812
PMC4198462
70 MS159 Association of Dysanapsis With Chronic Obstructive Pulmonary Disease Among Older Adults. Smith, Benjamin M.; Kirby, Miranda ; Hoffman, Eric A.; Kronmal, Richard A.; Aaron, Shawn D.; Allen, Norrina B.; Bertoni, Alain ; Coxson, Harvey O.; Cooper, Chris ; Couper, David J.; Criner, Gerard ; Dransfield, Mark T.; Han, Meilan K.; Hansel, Nadia N.; Jacobs, David R.; Kaufman, Joel D.; Lin, Ching-Long ; Manichaikul, Ani ; Martinez, Fernando J.; Michos, Erin D.; Oelsner, Elizabeth C.; Paine, Robert ; Watson, Karol E.; Benedetti, Andrea ; Tan, Wan C.; Bourbeau, Jean ; Woodruff, Prescott G.; Barr, Graham Clinical Center: New York (Columbia University) 2020 JAMA 32515814
PMC7284296
71 MS217 Risk of COPD exacerbation is increased by poor sleep quality and modified by social adversity. Baugh, Aaron ; Buhr, Russell G.; Quibrera, Pedro ; Barjaktarevic, Igor ; Barr, Graham ; Bowler, Russell ; Han, Meilan King; Kaufman, Joel D.; Koch, Abigail L.; Krishnan, Jerry ; Labaki, Wassim ; Martinez, Fernando J.; Mkorombindo, Takudzwa ; Namen, Andrew ; Ortega, Victor ; Paine, Robert ; Peters, Stephen P.; Schotland, Helena ; Sundar, Krishna ; Zeidler, Michelle R.; Hansel, Nadia N.; Woodruff, Prescott G.; Thakur, Neeta Clinical Center: San Francisco (University of California at San Francisco) 2022 Sleep 35665826
PMC9366643
72 MS144 Radiographic lung volumes predict progression to COPD in smokers with preserved spirometry in SPIROMICS. Arjomandi, Mehrdad ; Zeng, Siyang ; Barjaktarevic, Igor ; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Buhr, Russell G.; Criner, Gerard J.; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David J.; Curtis, Jeffrey L.; Dransfield, Mark T.; Han, Meilan K.; Hansel, Nadia N.; Hoffman, Eric A.; Kaner, Robert J.; Kanner, Richard E.; Krishnan, Jerry A.; Paine, Robert ; Peters, Stephen P.; Rennard, Stephen I.; Woodruff, Prescott G. Clinical Center: San Francisco (University of California at San Francisco) 2019 Eur Respir J 31439683
PMC7089627
73 MS113 Chronic lung disease in adult recurrent tuberculosis survivors in Zimbabwe: a cohort study. Chin, A T.; Rylance, J ; Makumbirofa, S ; Meffert, S ; Vu, T ; Clayton, J ; Mason, P ; Woodruff, P ; Metcalfe, J Clinical Center: San Francisco (University of California at San Francisco) 2019 Int J Tuberc Lung Dis 30808453
PMC6860915
74 MS081 An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup. Christenson, Stephanie A.; van den Berge, Maarten ; Faiz, Alen ; Inkamp, Kai ; Bhakta, Nirav ; Bonser, Luke R.; Zlock, Lorna T.; Barjaktarevic, Igor Z.; Barr, Graham ; Bleecker, Eugene R.; Boucher, Richard C.; Bowler, Russell P.; Comellas, Alejandro P.; Curtis, Jeffrey L.; Han, Meilan K.; Hansel, Nadia N.; Hiemstra, Pieter S.; Kaner, Robert J.; Krishnanm, Jerry A.; Martinez, Fernando J.; O'Neal, Wanda K.; Paine, Robert ; Timens, Wim ; Wells, Michael ; Spira, Avrum ; Erle, David J.; Woodruff, Prescott G. Clinical Center: San Francisco (University of California at San Francisco) 2019 J Clin Invest 30383540
PMC6307967
75 MS032 Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function. Woodruff, Prescott G.; Barr, Graham ; Bleecker, Eugene ; Christenson, Stephanie A.; Couper, David ; Curtis, Jeffrey L.; Gouskova, Natalia A.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Kleerup, Eric ; Lazarus, Stephen C.; Martinez, Fernando J.; Paine, Robert ; Rennard, Stephen ; Tashkin, Donald P.; Han, Meilan K. Clinical Center: San Francisco (University of California at San Francisco) 2016 N Engl J Med 27168432
PMC4968204
76 MS181 Elastin-Specific Autoimmunity in Smokers With Thoracic Aortic Aneurysm and Dissection is Independent of Chronic Obstructive Pulmonary Disease. Gu, Bon-Hee ; Choi, Justin C.; Shen, Ying H.; Song, Li-Zhen ; Scheurer, Michael E.; Luong, Amber ; Rodriguez, Antony ; Woodruff, Prescott ; Koth, Laura ; Corry, David B.; Kheradmand, Farrah ; LeMaire, Scott A. Clinical Center: San Francisco (University of California at San Francisco) 2019 J Am Heart Assoc 30957625
PMC6507218
77 MS190 Defining Resilience to Smoking-related Lung Disease: A Modified Delphi Approach from SPIROMICS. Oh, Anita L.; Mularski, Richard A.; Barjaktarevic, Igor ; Barr, Graham ; Bowler, Russell P.; Comellas, Alejandro P.; Cooper, Christopher B.; Criner, Gerard J.; Han, Meilan K.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Krishnan, Jerry A.; Paine, Robert ; Parekh, Trisha M.; Peters, Stephen P.; Christenson, Stephanie A.; Woodruff, Prescott G. Clinical Center: San Francisco (University of California at San Francisco) 2021 Ann Am Thorac Soc 33631079
PMC8641833
78 MS242 Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium. Kasela, Silva ; Ortega, Victor E.; Martorella, Molly ; Garudadri, Suresh ; Nguyen, Jenna ; Ampleford, Elizabeth ; Pasanen, Anu ; Nerella, Srilaxmi ; Buschur, Kristina L.; Barjaktarevic, Igor Z.; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David J.; Criner, Gerard J.; Curtis, Jeffrey L.; Han, Meilan K.; Hansel, Nadia N.; Hoffman, Eric A.; Kaner, Robert J.; Krishnan, Jerry A.; Martinez, Fernando J.; McDonald, Merry-Lynn N.; Meyers, Deborah A.; Paine, Robert ; Peters, Stephen P.; Castro, Mario ; Denlinger, Loren C.; Erzurum, Serpil C.; Fahy, John V.; Israel, Elliot ; Jarjour, Nizar N.; Levy, Bruce D.; Li, Xingnan ; Moore, Wendy C.; Wenzel, Sally E.; Zein, Joe ; Langelier, Charles ; Woodruff, Prescott G.; Lappalainen, Tuuli ; Christenson, Stephanie A. Clinical Center: San Francisco (University of California at San Francisco) 2021 Genome Med 33883027
PMC8059115
79 MS146 Systemic Markers of Inflammation in Smokers With Symptoms Despite Preserved Spirometry in SPIROMICS. Garudadri, Suresh ; Woodruff, Prescott G.; Han, Meilan K.; Curtis, Jeffrey L.; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Comellas, Alejandro ; Cooper, Christopher B.; Criner, Gerard ; Dransfield, Mark T.; Hansel, Nadia N.; Paine, Robert ; Krishnan, Jerry A.; Peters, Stephen P.; Hastie, Annette T.; Martinez, Fernando J.; O'Neal, Wanda K.; Couper, David J.; Alexis, Neil E.; Christenson, Stephanie A. Clinical Center: San Francisco (University of California at San Francisco) 2019 Chest 30684474
PMC6533449
80 MS183 Forced Expiratory Flow at 25%-75% Links COPD Physiology to Emphysema and Disease Severity in the SPIROMICS Cohort. Ronish, Bonnie E.; Couper, David J.; Barjaktarevic, Igor Z.; Cooper, Christopher B.; Kanner, Richard E.; Pirozzi, Cheryl S.; Kim, Victor ; Wells, James M.; Han, Meilan K.; Woodruff, Prescott G.; Ortega, Victor E.; Peters, Stephen P.; Hoffman, Eric A.; Buhr, Russell G.; Dolezal, Brett A.; Tashkin, Donald P.; Liou, Theodore G.; Bateman, Lori A.; Schroeder, Joyce D.; Martinez, Fernando J.; Barr, Graham ; Hansel, Nadia N.; Comellas, Alejandro P.; Rennard, Stephen I.; Arjomandi, Mehrdad ; Iii, Robert Paine Clinical Center: Utah (University of Utah) 2022 Chronic Obstr Pulm Dis 35114743
PMC9166328
81 MS041 Heterogeneous burden of lung disease in smokers with borderline airflow obstruction. Pirozzi, Cheryl S.; Gu, Tian ; Quibrera, Pedro M.; Carretta, Elizabeth E.; Han, Meilan K.; Murray, Susan ; Cooper, Christopher B.; Tashkin, Donald P.; Kleerup, Eric C.; Barjaktarevic, Igor ; Hoffman, Eric A.; Martinez, Carlos H.; Christenson, Stephanie A.; Hansel, Nadia N.; Barr, Graham ; Bleecker, Eugene R.; Ortega, Victor E.; Martinez, Fernando J.; Kanner, Richard E.; Paine, Robert Clinical Center: Utah (University of Utah) 2018 Respir Res 30454050
PMC6245799
82 MS072 Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. Hobbs, Brian D.; de Jong, Kim ; Lamontagne, Maxime ; Bossé, Yohan ; Shrine, Nick ; Artigas, María Soler; Wain, Louise V.; Hall, Ian P.; Jackson, Victoria E.; Wyss, Annah B.; London, Stephanie J.; North, Kari E.; Franceschini, Nora ; Strachan, David P.; Beaty, Terri H.; Hokanson, John E.; Crapo, James D.; Castaldi, Peter J.; Chase, Robert P.; Bartz, Traci M.; Heckbert, Susan R.; Psaty, Bruce M.; Gharib, Sina A.; Zanen, Pieter ; Lammers, Jan W.; Oudkerk, Matthijs ; Groen, H J.; Locantore, Nicholas ; Tal-Singer, Ruth ; Rennard, Stephen I.; Vestbo, Jørgen ; Timens, Wim ; Paré, Peter D.; Latourelle, Jeanne C.; Dupuis, Josée ; O'Connor, George T.; Wilk, Jemma B.; Kim, Woo Jin; Lee, Mi Kyeong; Oh, Yeon-Mok ; Vonk, Judith M.; de Koning, Harry J.; Leng, Shuguang ; Belinsky, Steven A.; Tesfaigzi, Yohannes ; Manichaikul, Ani ; Wang, Xin-Qun ; Rich, Stephen S.; Barr, Graham ; Sparrow, David ; Litonjua, Augusto A.; Bakke, Per ; Gulsvik, Amund ; Lahousse, Lies ; Brusselle, Guy G.; Stricker, Bruno H.; Uitterlinden, André G.; Ampleford, Elizabeth J.; Bleecker, Eugene R.; Woodruff, Prescott G.; Meyers, Deborah A.; Qiao, Dandi ; Lomas, David A.; Yim, Jae-Joon ; Kim, Deog Kyeom; Hawrylkiewicz, Iwona ; Sliwinski, Pawel ; Hardin, Megan ; Fingerlin, Tasha E.; Schwartz, David A.; Postma, Dirkje S.; MacNee, William ; Tobin, Martin D.; Silverman, Edwin K.; Boezen, Marike ; Cho, Michael H. Clinical Center: Winston-Salem (Wake Forest University Health Sciences) 2017 Nat Genet 28166215
PMC5381275
83 MS023 The Effects of Rare Variants on Lung Function and Emphysema in SPIROMICS. Ortega, Victor E.; Li, Xingnan ; O'Neal, Wanda K.; Lackey, Lela ; Ampleford, Elizabeth ; Hawkins, Gregory A.; Grayeski, Philip J.; Laederach, Alain ; Barjaktarevic, Igor ; Barr, Graham ; Cooper, Christopher ; Couper, David ; Han, Meilan K.; Kanner, Richard E.; Kleerup, Eric C.; Martinez, Fernando J.; Paine, Robert ; Peters, Stephen P.; Pirozzi, Cheryl ; Rennard, Stephen I.; Woodruff, Prescott G.; Hoffman, Eric A.; Meyers, Deborah A.; Bleecker, Eugene R. Clinical Center: Winston-Salem (Wake Forest University Health Sciences) 2020 Am J Respir Crit Care Med 31661293
PMC7047460
84 MS029 Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort. Hastie, Annette T.; Martinez, Fernando J.; Curtis, Jeffrey L.; Doerschuk, Claire M.; Hansel, Nadia N.; Christenson, Stephanie ; Putcha, Nirupama ; Ortega, Victor E.; Li, Xingnan ; Barr, Graham ; Carretta, Elizabeth E.; Couper, David J.; Cooper, Christopher B.; Hoffman, Eric A.; Kanner, Richard E.; Kleerup, Eric ; O'Neal, Wanda K.; Paine, Richard ; Peters, Stephen P.; Alexis, Neil E.; Woodruff, Prescott G.; Han, Meilan K.; Meyers, Deborah A.; Bleecker, Eugene R. Clinical Center: Winston-Salem (Wake Forest University Health Sciences) 2017 Lancet Respir Med 29146301
PMC5849066
85 MS005 Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study. O'Neal, Wanda K.; Anderson, Wayne ; Basta, Patricia V.; Carretta, Elizabeth E.; Doerschuk, Claire M.; Barr, Graham ; Bleecker, Eugene R.; Christenson, Stephanie A.; Curtis, Jeffrey L.; Han, Meilan K.; Hansel, Nadia N.; Kanner, Richard E.; Kleerup, Eric C.; Martinez, Fernando J.; Miller, Bruce E.; Peters, Stephen P.; Rennard, Stephen I.; Scholand, Mary Beth; Tal-Singer, Ruth ; Woodruff, Prescott G.; Couper, David J.; Davis, Sonia M. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2014 J Transl Med 24397870
PMC3928911
86 MS094 Alignment of Inhaled Chronic Obstructive Pulmonary Disease Therapies with Published Strategies. Analysis of the Global Initiative for Chronic Obstructive Lung Disease Recommendations in SPIROMICS. Ghosh, Sohini ; Anderson, Wayne H.; Putcha, Nirupama ; Han, Meilan K.; Curtis, Jeffrey L.; Criner, Gerard J.; Dransfield, Mark T.; Barr, Graham ; Krishnan, Jerry A.; Lazarus, Stephen C.; Cooper, Christopher B.; Paine, Robert ; Peters, Stephen P.; Hansel, Nadia N.; Martinez, Fernando J.; Drummond, Bradley Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2019 Ann Am Thorac Soc 30216731
PMC6376942
87 MS002 Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). Couper, David ; LaVange, Lisa M.; Han, MeiLan ; Barr, Graham ; Bleecker, Eugene ; Hoffman, Eric A.; Kanner, Richard ; Kleerup, Eric ; Martinez, Fernando J.; Woodruff, Prescott G.; Rennard, Stephen Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2014 Thorax 24029743
PMC3954445
88 MS016 Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD. Sun, Wei ; Kechris, Katerina ; Jacobson, Sean ; Drummond, Bradley ; Hawkins, Gregory A.; Yang, Jenny ; Chen, Ting-Huei ; Quibrera, Pedro Miguel; Anderson, Wayne ; Barr, Graham ; Basta, Patricia V.; Bleecker, Eugene R.; Beaty, Terri ; Casaburi, Richard ; Castaldi, Peter ; Cho, Michael H.; Comellas, Alejandro ; Crapo, James D.; Criner, Gerard ; Demeo, Dawn ; Christenson, Stephanie A.; Couper, David J.; Curtis, Jeffrey L.; Doerschuk, Claire M.; Freeman, Christine M.; Gouskova, Natalia A.; Han, Meilan K.; Hanania, Nicola A.; Hansel, Nadia N.; Hersh, Craig P.; Hoffman, Eric A.; Kaner, Robert J.; Kanner, Richard E.; Kleerup, Eric C.; Lutz, Sharon ; Martinez, Fernando J.; Meyers, Deborah A.; Peters, Stephen P.; Regan, Elizabeth A.; Rennard, Stephen I.; Scholand, Mary Beth; Silverman, Edwin K.; Woodruff, Prescott G.; O'Neal, Wanda K.; Bowler, Russell P. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2016 PLoS Genet 27532455
PMC4988780
89 MS082 Airway Mucin Concentration as a Marker of Chronic Bronchitis. Kesimer, Mehmet ; Ford, Amina A.; Ceppe, Agathe ; Radicioni, Giorgia ; Cao, Rui ; Davis, William ; Doerschuk, Claire M.; Alexis, Neil E.; Anderson, Wayne H.; Henderson, Ashley G.; Barr, Graham ; Bleecker, Eugene R.; Christenson, Stephanie A.; Cooper, Christopher B.; Han, Meilan K.; Hansel, Nadia N.; Hastie, Annette T.; Hoffman, Eric A.; Kanner, Richard E.; Martinez, Fernando ; Paine, Robert ; Woodruff, Prescott G.; O'Neal, Wanda K.; Boucher, Richard C. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2017 N Engl J Med 28877023
PMC5706541
90 MS210 Prolonged, Physiologically Relevant Nicotine Concentrations in the Airways of Smokers Esther, Charles R.; O'Neal, Wanda K.; Alexis, Neil E.; Koch, Abigail L.; Cooper, Christopher B.; Barjaktarevic, Igor ; Raffield, Laura M.; Bowler, Russell P.; Comellas, Alejandro P.; Peters, Stephen P.; Hastie, Annette T.; Curtis, Jeffrey L.; Ronish, Bonnie ; Ortega, Victor E.; Wells, Michael ; Halper-Stromberg, Eitan ; Rennard, Stephen I.; Boucher, Richard C. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2022 Am J Physiol Lung Cell Mol Physiol 36342131
91 MS116 Plasma Cathelicidin is Independently Associated with Reduced Lung Function in COPD: Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort. Burkes, Robert M.; Ceppe, Agathe S.; Couper, David J.; Comellas, Alejandro P.; Wells, Michael ; Peters, Stephen P.; Criner, Gerard J.; Kanner, Richard E.; Paine, Robert ; Christenson, Stephanie A.; Cooper, Christopher B.; Barjaktarevic, Igor Z.; Krishnan, Jerry A.; Labaki, Wassim W.; Han, Meilan K.; Curtis, Jeffrey L.; Hansel, Nadia N.; Wise, Robert A.; Drummond, Bradley Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2020 Chronic Obstr Pulm Dis 33108110
PMC7883905
92 MS219 Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. Radicioni, Giorgia ; Ceppe, Agathe ; Ford, Amina A.; Alexis, Neil E.; Barr, Graham ; Bleecker, Eugene R.; Christenson, Stephanie A.; Cooper, Christopher B.; Han, Meilan K.; Hansel, Nadia N.; Hastie, Annette T.; Hoffman, Eric A.; Kanner, Richard E.; Martinez, Fernando J.; Ozkan, Esin ; Paine, Robert ; Woodruff, Prescott G.; O'Neal, Wanda K.; Boucher, Richard C.; Kesimer, Mehmet Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2021 Lancet Respir Med 34058148
PMC8570975
93 MS150 Comparison of Proteomic Assessment Methods in Multiple Cohort Studies. Raffield, Laura M.; Dang, Hong ; Pratte, Katherine A.; Jacobson, Sean ; Gillenwater, Lucas A.; Ampleford, Elizabeth ; Barjaktarevic, Igor ; Basta, Patricia ; Clish, Clary B.; Comellas, Alejandro P.; Cornell, Elaine ; Curtis, Jeffrey L.; Doerschuk, Claire ; Durda, Peter ; Emson, Claire ; Freeman, Christine M.; Guo, Xiuqing ; Hastie, Annette T.; Hawkins, Gregory A.; Herrera, Julio ; Johnson, Craig ; Labaki, Wassim W.; Liu, Yongmei ; Masters, Brett ; Miller, Michael ; Ortega, Victor E.; Papanicolaou, George ; Peters, Stephen ; Taylor, Kent D.; Rich, Stephen S.; Rotter, Jerome I.; Auer, Paul ; Reiner, Alex P.; Tracy, Russell P.; Ngo, Debby ; Gerszten, Robert E.; O'Neal, Wanda K.; Bowler, Russell P. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2020 Proteomics 32386347
PMC7425176
94 MS056 Variability in objective and subjective measures affects baseline values in studies of patients with COPD. Anderson, Wayne H.; Ha, Jae Wook; Couper, David J.; O'Neal, Wanda K.; Barr, Graham ; Bleecker, Eugene R.; Carretta, Elizabeth E.; Cooper, Christopher B.; Doerschuk, Claire M.; Drummond, Bradley ; Han, Meilan K.; Hansel, Nadia N.; Kim, Victor ; Kleerup, Eric C.; Martinez, Fernando J.; Rennard, Stephen I.; Tashkin, Donald ; Woodruff, Prescott G.; Paine, Robert ; Curtis, Jeffrey L.; Kanner, Richard E. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2017 PLoS One 28934249
PMC5608200
95 MS082 Mucin Concentrations and Peripheral Airway Obstruction in Chronic Obstructive Pulmonary Disease. Kesimer, Mehmet ; Smith, Benjamin M.; Ceppe, Agathe ; Ford, Amina A.; Anderson, Wayne H.; Barr, Graham ; O'Neal, Wanda K.; Boucher, Richard C. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2018 Am J Respir Crit Care Med 30130124
PMC6290944
96 MS158 Associations Among 25-Hydroxyvitamin D Levels, Lung Function, and Exacerbation Outcomes in COPD: An Analysis of the SPIROMICS Cohort. Burkes, Robert M.; Ceppe, Agathe S.; Doerschuk, Claire M.; Couper, David ; Hoffman, Eric A.; Comellas, Alejandro P.; Barr, Graham ; Krishnan, Jerry A.; Cooper, Christopher ; Labaki, Wassim W.; Ortega, Victor E.; Wells, Michael ; Criner, Gerard J.; Woodruff, Prescott G.; Bowler, Russell P.; Pirozzi, Cheryl S.; Hansel, Nadia N.; Wise, Robert A.; Brown, Todd T.; Drummond, Bradley Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2020 Chest 31958447
PMC7118244
97 MS092 Rural Residence and Chronic Obstructive Pulmonary Disease Exacerbations. Analysis of the SPIROMICS Cohort. Burkes, Robert M.; Gassett, Amanda J.; Ceppe, Agathe S.; Anderson, Wayne ; O'Neal, Wanda K.; Woodruff, Prescott G.; Krishnan, Jerry A.; Barr, Graham ; Han, Meilan K.; Martinez, Fernando J.; Comellas, Alejandro P.; Lambert, Allison A.; Kaufman, Joel D.; Dransfield, Mark T.; Wells, Michael ; Kanner, Richard E.; Paine, Robert ; Bleecker, Eugene R.; Paulin, Laura M.; Hansel, Nadia N.; Drummond, Bradley Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2018 Ann Am Thorac Soc 29584453
PMC6207115
98 MS158 Age-Dependent Associations Between 25-Hydroxy Vitamin D Levels and COPD Symptoms: Analysis of SPIROMICS. Burkes, Robert M.; Couper, David J.; Barjaktarevic, Igor Z.; Cooper, Christopher B.; Labaki, Wassim W.; Han, Meilan K.; Woodruff, Prescott G.; Lazarus, Stephen C.; Parekh, Trisha M.; Paine, Robert ; Comellas, Alejandro P.; Bowler, Russell P.; Loehr, Laura R.; Putcha, Nirupama ; Wise, Robert A.; Brown, Todd T.; Drummond, Bradley Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2021 Chronic Obstr Pulm Dis 33829714
PMC8237982
99 MS001 The COPD ontology and toward empowering clinical scientists as ontology engineers greenberg, jane ; O'Neal, Wanda ; Deshmukh, Rahul ; Lina, Huang ; Mostafa, Javed ; LaVange, Lisa M.; Carretta, Elizabeth E. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2010 Journal of Library Metadata
100 MS008 SPIROMICS Protocol for Multicenter Quantitative Computed Tomography to Phenotype the Lungs. Sieren, Jered P.; Newell, John D.; Barr, Graham ; Bleecker, Eugene R.; Burnette, Nathan ; Carretta, Elizabeth E.; Couper, David ; Goldin, Jonathan ; Guo, Junfeng ; Han, Meilan K.; Hansel, Nadia N.; Kanner, Richard E.; Kazerooni, Ella A.; Martinez, Fernando J.; Rennard, Stephen ; Woodruff, Prescott G.; Hoffman, Eric A. Reading Center: Radiology (University of Iowa) 2016 Am J Respir Crit Care Med 27482984
PMC5074650
101 MS261 PLOSL: Population learning followed by one shot learning pulmonary image registration using tissue volume preserving and vesselness constraints. Wang, Di ; Pan, Yue ; Durumeric, Oguz C.; Reinhardt, Joseph M.; Hoffman, Eric A.; Schroeder, Joyce D.; Christensen, Gary E. Reading Center: Radiology (University of Iowa) 2022 Med Image Anal 35430476
102 MS103 Imaging-based clusters in current smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Haghighi, Babak ; Choi, Sanghun ; Choi, Jiwoong ; Hoffman, Eric A.; Comellas, Alejandro P.; Newell, John D.; Barr, Graham ; Bleecker, Eugene ; Cooper, Christopher B.; Couper, David ; Han, Mei Lan; Hansel, Nadia N.; Kanner, Richard E.; Kazerooni, Ella A.; Kleerup, Eric A.C.; Martinez, Fernando J.; O'Neal, Wanda ; Rennard, Stephen I.; Woodruff, Prescott G.; Lin, Ching-Long Reading Center: Radiology (University of Iowa) 2018 Respir Res 30227877
PMC6145340
103 MS212 Robust Measures of Image-Registration-Derived Lung Biomechanics in SPIROMICS Pan, Yue ; Wang, Di ; Chaudhary, Muhammad F.A.; Shao, Wei ; Gerard, Sarah E.; Durumeric, Oguz C.; Bhatt, Surya P.; Barr, Graham ; Hoffman, Eric A.; Reinhardt, Joseph M.; Christensen, Gary E. Reading Center: Radiology (University of Iowa) 2022 J Imaging 36422058
PMC9693030
104 MS182 Structural and Functional Features on Quantitative Chest Computed Tomography in the Korean Asian versus the White American Healthy Non-Smokers. Bin Cho, Hyun ; Chae, Kum Ju; Jin, Gong Yong; Choi, Jiwoong ; Lin, Ching Long; Hoffman, Eric A.; Wenzel, Sally E.; Castro, Mario ; Fain, Sean B.; Jarjour, Nizar N.; Schiebler, Mark L.; Barr, Graham ; Hansel, Nadia ; Cooper, Christopher B.; Kleerup, Eric C.; Han, Meilan K.; Woodruff, Prescott G.; Kanner, Richard E.; Bleecker, Eugene R.; Peters, Stephen P.; Moore, Wendy C.; Lee, Chang Hyun; Choi, Sanghun Reading Center: Radiology (University of Iowa) 2019 Korean J Radiol 31270987
PMC6609438
105 MS008 Comparison of low- and ultralow-dose computed tomography protocols for quantitative lung and airway assessment. Hammond, Emily ; Sloan, Chelsea ; Newell, John D.; Sieren, Jered P.; Saylor, Melissa ; Vidal, Craig ; Hogue, Shayna ; De Stefano, Frank ; Sieren, Alexa ; Hoffman, Eric A.; Sieren, Jessica C. Reading Center: Radiology (University of Iowa) 2017 Med Phys 28657201
PMC5603212
106 MS170 Increased airway iron parameters and risk for exacerbation in COPD: an analysis from SPIROMICS. Zhang, William Z.; Oromendia, Clara ; Kikkers, Sarah Ann; Butler, James J.; O'Beirne, Sarah ; Kim, Kihwan ; O'Neal, Wanda K.; Freeman, Christine M.; Christenson, Stephanie A.; Peters, Stephen P.; Wells, Michael ; Doerschuk, Claire ; Putcha, Nirupama ; Barjaktarevic, Igor ; Woodruff, Prescott G.; Cooper, Christopher B.; Bowler, Russell P.; Comellas, Alejandro P.; Criner, Gerard J.; Paine, Robert ; Hansel, Nadia N.; Han, Meilan K.; Crystal, Ronald G.; Kaner, Robert J.; Ballman, Karla V.; Curtis, Jeffrey L.; Martinez, Fernando J.; Cloonan, Suzanne M. Weill Cornell Medical Center 2020 Sci Rep 32601308
PMC7324559
107 MS067 Characterizing COPD Symptom Variability in the Stable State Utilizing the Evaluating Respiratory Symptoms in COPD Instrument. Krishnan, Jamuna K.; Ancy, Kayley M.; Oromendia, Clara ; Hoffman, Katherine L.; Easthausen, Imaani ; Leidy, Nancy K.; Han, Meilan K.; Bowler, Russell P.; Christenson, Stephanie A.; Couper, David J.; Criner, Gerard J.; Curtis, Jeffrey L.; Dransfield, Mark T.; Hansel, Nadia N.; Iyer, Anand S.; Iii, Robert Paine; Peters, Stephen P.; Wedzicha, Jadwiga A.; Woodruff, Prescott G.; Ballman, Karla V.; Martinez, Fernando J. Weill Cornell Medical Center 2022 Chronic Obstr Pulm Dis 35403414
PMC9166327
108 MS194 Association of plasma mitochondrial DNA with COPD severity and progression in the SPIROMICS cohort. Zhang, William Z.; Hoffman, Katherine L.; Schiffer, Kristen T.; Oromendia, Clara ; Rice, Michelle C.; Barjaktarevic, Igor ; Peters, Stephen P.; Putcha, Nirupama ; Bowler, Russell P.; Wells, Michael ; Couper, David J.; Labaki, Wassim W.; Curtis, Jeffrey L.; Han, Meilan K.; Paine, Robert ; Woodruff, Prescott G.; Criner, Gerard J.; Hansel, Nadia N.; Diaz, Ivan ; Ballman, Karla V.; Nakahira, Kiichi ; Choi, Mary E.; Martinez, Fernando J.; Choi, Augustine M.K.; Cloonan, Suzanne M. Weill Cornell Medical Center 2021 Respir Res 33902556
PMC8074408
109 MS194 Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort. Zhang, William Z.; Rice, Michelle C.; Hoffman, Katherine L.; Oromendia, Clara ; Barjaktarevic, Igor Z.; Wells, Michael ; Hastie, Annette T.; Labaki, Wassim W.; Cooper, Christopher B.; Comellas, Alejandro P.; Criner, Gerard J.; Krishnan, Jerry A.; Paine, Robert ; Hansel, Nadia N.; Bowler, Russell P.; Barr, Graham ; Peters, Stephen P.; Woodruff, Prescott G.; Curtis, Jeffrey L.; Han, Meilan K.; Ballman, Karla V.; Martinez, Fernando J.; Choi, Augustine Mk; Nakahira, Kiichi ; Cloonan, Suzanne M.; Choi, Mary E. Weill Cornell Medical Center 2020 JCI Insight 31895696
PMC7098791
110 MS073 Genome-wide association study of lung function and clinical implication in heavy smokers. Li, Xingnan ; Ortega, Victor E.; Ampleford, Elizabeth J.; Barr, Graham ; Christenson, Stephanie A.; Cooper, Christopher B.; Couper, David ; Dransfield, Mark T.; Han, Mei Lan K.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Kleerup, Eric C.; Martinez, Fernando J.; Paine, Robert ; Woodruff, Prescott G.; Hawkins, Gregory A.; Bleecker, Eugene R.; Meyers, Deborah A. Clinical Center: Tucson (University of Arizona) 2018 BMC Med Genet 30068317
PMC6090900
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