Manuscripts Published

28 rows
# Number Title Authors Site Year Journal Links
1 MS051 Age and Small Airway Imaging Abnormalities in Subjects with and without Airflow Obstruction in SPIROMICS. Martinez, Carlos H.; Diaz, Alejandro A.; Meldrum, Catherine ; Curtis, Jeffrey L.; Cooper, Christopher B.; Pirozzi, Cheryl ; Kanner, Richard E.; Paine, Robert ; Woodruff, Prescott G.; Bleecker, Eugene R.; Hansel, Nadia N.; Barr, Graham ; Marchetti, Nathaniel ; Criner, Gerard J.; Kazerooni, Ella A.; Hoffman, Eric A.; Ross, Brian D.; Galbán, Craig J.; Cigolle, Christine T.; Martinez, Fernando J.; Han, Meilan K. Clinical Center: Michigan (University of Michigan) 2017 Am J Respir Crit Care Med 27564413
PMC5378423
2 MS082 Airway Mucin Concentration as a Marker of Chronic Bronchitis Kesimer, Mehmet ; Ford, Amina A.; Ceppe, Agathe ; Radicioni, Giorgia ; Cao, Rui ; Davis, William ; Doerschuk, Claire M.; Alexis, Neil E.; Anderson, Wayne H.; Henderson, Ashley G.; Barr, Graham ; Bleecker, Eugene R.; Christenson, Stephanie A.; Cooper, Christopher B.; Han, Meilan K.; Hansel, Nadia N.; Hastie, Annette T.; Hoffman, Eric A.; Kanner, Richard E.; Martinez, Fernando ; Paine, Robert ; Woodruff, Prescott G.; O'Neal, Wanda K.; Boucher, Richard C. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2017 N Engl J Med 28877023
3 MS080 Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort. Martinez, Carlos H.; Li, Sara X.; Hirzel, Andrew J.; Stolberg, Valerie R.; Alexis, Neil E.; Barr, Graham ; Bleecker, Eugene R.; Carretta, Elizabeth E.; Christenson, Stephanie A.; Cooper, Christopher B.; Couper, David J.; Doerschuk, Claire M.; Han, Meilan K.; Hansel, Nadia N.; Hastie, Annette T.; Hoffman, Eric A.; Kaner, Robert J.; Martinez, Fernando J.; Meyers, Deborah A.; O'Neal, Wanda K.; Paine, Robert ; Putcha, Nirupama ; Rennard, Stephen I.; Woodruff, Prescott G.; Zeidler, Michelle ; Curtis, Jeffrey L.; Freeman, Christine M. Clinical Center: Michigan (University of Michigan) 2017 J Allergy Clin Immunol 28916185
4 MS029 Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort. Hastie, Annette T.; Martinez, Fernando J.; Curtis, Jeffrey L.; Doerschuk, Claire M.; Hansel, Nadia N.; Christenson, Stephanie ; Putcha, Nirupama ; Ortega, Victor E.; Li, Xingnan ; Barr, Graham ; Carretta, Elizabeth E.; Couper, David J.; Cooper, Christopher B.; Hoffman, Eric A.; Kanner, Richard E.; Kleerup, Eric ; O'Neal, Wanda K.; Paine, Richard ; Peters, Stephen P.; Alexis, Neil E.; Woodruff, Prescott G.; Han, Meilan K.; Meyers, Deborah A.; Bleecker, Eugene R. Clinical Center: Winston-Salem (Wake Forest University Health Sciences) 2017 Lancet Respir Med 29146301
5 MS026 Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts. Keene, Jason D.; Jacobson, Sean ; Kechris, Katerina ; Kinney, Gregory L.; Foreman, Marilyn G.; Doerschuk, Claire M.; Make, Barry J.; Curtis, Jeffrey L.; Rennard, Stephen I.; Barr, Graham ; Bleecker, Eugene R.; Kanner, Richard E.; Kleerup, Eric C.; Hansel, Nadia N.; Woodruff, Prescott G.; Han, Meilan K.; Paine, Robert ; Martinez, Fernando J.; Bowler, Russell P.; O'Neal, Wanda K. Clinical Center: Denver (National Jewish Health) 2017 Am J Respir Crit Care Med 27579823
PMC5378424
6 MS045 Cigarette smoke disrupts monolayer integrity by altering epithelial cell-cell adhesion and cortical tension. Nishida, Kristine ; Brune, Kieran A.; Putcha, Nirupama ; Mandke, Pooja ; O'Neal, Wanda K.; Shade, Danny ; Srivastava, Vasudha ; Wang, Menghan ; Lam, Hong ; An, Steven S.; Drummond, Bradley ; Hansel, Nadia N.; Robinson, Douglas N.; Sidhaye, Venkataramana K. Clinical Center: Baltimore (Johns Hopkins University) 2017 Am J Physiol Lung Cell Mol Physiol 28642260
PMC5625260
7 MS008 Comparison of low- and ultralow-dose computed tomography protocols for quantitative lung and airway assessment. Hammond, Emily ; Sloan, Chelsea ; Newell, John D.; Sieren, Jered P.; Saylor, Melissa ; Vidal, Craig ; Hogue, Shayna ; De Stefano, Frank ; Sieren, Alexa ; Hoffman, Eric A.; Sieren, Jessica C. Reading Center: Radiology (University of Iowa) 2017 Med Phys 28657201
PMC5603212
8 MS083 Electronic Cigarette Use in US Adults at Risk for or with COPD: Analysis from Two Observational Cohorts. Bowler, Russell P.; Hansel, Nadia N.; Jacobson, Sean ; Barr, Graham ; Make, Barry J.; Han, Meilan K.; O'Neal, Wanda K.; Oelsner, Elizabeth C.; Casaburi, Richard ; Barjaktarevic, Igor ; Cooper, Chris ; Foreman, Marilyn ; Wise, Robert A.; DeMeo, Dawn L.; Silverman, Edwin K.; Bailey, William ; Harrington, Kathleen F.; Woodruff, Prescott G.; Drummond, Bradley Clinical Center: Denver (National Jewish Health) 2017 J Gen Intern Med 28884423
9 MS034 Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. Han, Meilan K.; Quibrera, Pedro M.; Carretta, Elizabeth E.; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Cooper, Christopher B.; Comellas, Alejandro ; Couper, David J.; Curtis, Jeffrey L.; Criner, Gerard ; Dransfield, Mark T.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Krishnan, Jerry A.; Martinez, Carlos H.; Pirozzi, Cheryl B.; O'Neal, Wanda K.; Rennard, Stephen ; Tashkin, Donald P.; Wedzicha, Jadwiga A.; Woodruff, Prescott ; Paine, Robert ; Martinez, Fernando J. Clinical Center: Michigan (University of Michigan) 2017 Lancet Respir Med 28668356
PMC5558856
10 MS072 Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. Hobbs, Brian D.; de Jong, Kim ; Lamontagne, Maxime ; Bossé, Yohan ; Shrine, Nick ; Artigas, María Soler; Wain, Louise V.; Hall, Ian P.; Jackson, Victoria E.; Wyss, Annah B.; London, Stephanie J.; North, Kari E.; Franceschini, Nora ; Strachan, David P.; Beaty, Terri H.; Hokanson, John E.; Crapo, James D.; Castaldi, Peter J.; Chase, Robert P.; Bartz, Traci M.; Heckbert, Susan R.; Psaty, Bruce M.; Gharib, Sina A.; Zanen, Pieter ; Lammers, Jan W.; Oudkerk, Matthijs ; Groen, H J.; Locantore, Nicholas ; Tal-Singer, Ruth ; Rennard, Stephen I.; Vestbo, Jørgen ; Timens, Wim ; Paré, Peter D.; Latourelle, Jeanne C.; Dupuis, Josée ; O'Connor, George T.; Wilk, Jemma B.; Kim, Woo Jin; Lee, Mi Kyeong; Oh, Yeon-Mok ; Vonk, Judith M.; de Koning, Harry J.; Leng, Shuguang ; Belinsky, Steven A.; Tesfaigzi, Yohannes ; Manichaikul, Ani ; Wang, Xin-Qun ; Rich, Stephen S.; Barr, Graham ; Sparrow, David ; Litonjua, Augusto A.; Bakke, Per ; Gulsvik, Amund ; Lahousse, Lies ; Brusselle, Guy G.; Stricker, Bruno H.; Uitterlinden, André G.; Ampleford, Elizabeth J.; Bleecker, Eugene R.; Woodruff, Prescott G.; Meyers, Deborah A.; Qiao, Dandi ; Lomas, David A.; Yim, Jae-Joon ; Kim, Deog Kyeom; Hawrylkiewicz, Iwona ; Sliwinski, Pawel ; Hardin, Megan ; Fingerlin, Tasha E.; Schwartz, David A.; Postma, Dirkje S.; MacNee, William ; Tobin, Martin D.; Silverman, Edwin K.; Boezen, Marike ; Cho, Michael H. Clinical Center: Winston-Salem (Wake Forest University Health Sciences) 2017 Nat Genet 28166215
PMC5381275
11 MS078 Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort. Martinez, Carlos H.; Murray, Susan ; Barr, Graham ; Bleecker, Eugene ; Bowler, Russell P.; Christenson, Stephanie A.; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David ; Criner, Gerard J.; Curtis, Jeffrey L.; Dransfield, Mark T.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Kleerup, Eric ; Krishnan, Jerry A.; Lazarus, Stephen C.; Leidy, Nancy K.; O'Neal, Wanda ; Martinez, Fernando J.; Paine, Robert ; Rennard, Stephen I.; Tashkin, Donald P.; Woodruff, Prescott G.; Han, Meilan K. Clinical Center: Michigan (University of Michigan) 2017 Ann Am Thorac Soc 28459622
PMC5427740
12 MS075 Subpopulations and Intermediate Outcomes in COPD (SPIROMICS) Air Pollution Study Design Hansel, Nadia N.; Paulin, Laura M.; Amanda, Gassett ; Roger, Peng ; Alexis, Neil E.; Fan, Vincent ; Bleecker, Eugene ; Bowler, Russell P.; Comellas, Alejandro P.; Dransfield, Mark T.; Han, Meilan K.; Kim, Victor ; Krishnan, Jerry A.; Pirozzi, Cheryl ; Cooper, Christopher B.; Martinez, Fernando J.; Woodruff, Prescott G.; Patrick, Breysse ; Barr, Graham ; Kaufman, Joel Clinical Center: Baltimore (Johns Hopkins University) 2017 BJM Open Respiratory Research
13 MS107 The utility of cytokines and chemokines in assessing COPD Bradford, Eric ; Jacobson, Sean ; Varasteh, Jason ; Comellas, Alejandro P.; Woodruff, Prescott ; O'Neal, Wanda ; DeMeo, Dawn L.; Li, Xingnan ; Kim, Victor ; Cho, Michael ; Castaldi, Peter J.; Hersh, Craig ; Silverman, Edwin K.; Crapo, James D.; Kechris, Katerina ; Bowler, Russell P. Clinical Center: Denver (National Jewish Health) 2017 Respir Res 29065892
PMC5655820
14 MS056 Variability in objective and subjective measures affects baseline values in studies of patients with COPD. Anderson, Wayne H.; Ha, Jae Wook; Couper, David J.; O'Neal, Wanda K.; Barr, Graham ; Bleecker, Eugene R.; Carretta, Elizabeth E.; Cooper, Christopher B.; Doerschuk, Claire M.; Drummond, Bradley ; Han, Meilan K.; Hansel, Nadia N.; Kim, Victor ; Kleerup, Eric C.; Martinez, Fernando J.; Rennard, Stephen I.; Tashkin, Donald ; Woodruff, Prescott G.; Paine, Robert ; Curtis, Jeffrey L.; Kanner, Richard E. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2017 PLoS One 28934249
PMC5608200
15 MS068 A controlled statistical study to assess measurement variability as a function of test object position and configuration for automated surveillance in a multicenter longitudinal COPD study (SPIROMICS). Guo, Junfeng ; Wang, Chao ; Chan, Kung-Sik ; Jin, Dakai ; Saha, Punam K.; Sieren, Jered P.; Barr, R G.; Han, Meilan K.; Kazerooni, Ella ; Cooper, Christopher B.; Couper, David ; Newell, John D.; Hoffman, Eric A. Clinical Center: Iowa (University of Iowa) 2016 Med Phys 27147369
PMC4851622
16 MS036 Age-Related Differences in Health-Related Quality of Life in COPD: An Analysis of the COPDGene and SPIROMICS Cohorts. Martinez, Carlos H.; Diaz, Alejandro A.; Parulekar, Amit D.; Rennard, Stephen I.; Kanner, Richard E.; Hansel, Nadia N.; Couper, David ; Holm, Kristen E.; Hoth, Karin F.; Curtis, Jeffrey L.; Martinez, Fernando J.; Hanania, Nicola A.; Regan, Elizabeth A.; Paine, Robert ; Cigolle, Christine T.; Han, Meilan K. Clinical Center: Michigan (University of Michigan) 2016 Chest 26836895
PMC4944781
17 MS032 Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function. Woodruff, Prescott G.; Barr, Graham ; Bleecker, Eugene ; Christenson, Stephanie A.; Couper, David ; Curtis, Jeffrey L.; Gouskova, Natalia A.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Kleerup, Eric ; Lazarus, Stephen C.; Martinez, Fernando J.; Paine, Robert ; Rennard, Stephen ; Tashkin, Donald P.; Han, Meilan K. Clinical Center: San Francisco (University of California at San Francisco) 2016 N Engl J Med 27168432
PMC4968204
18 MS016 Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD. Sun, Wei ; Kechris, Katerina ; Jacobson, Sean ; Drummond, Bradley ; Hawkins, Gregory A.; Yang, Jenny ; Chen, Ting-Huei ; Quibrera, Pedro Miguel; Anderson, Wayne ; Barr, Graham ; Basta, Patricia V.; Bleecker, Eugene R.; Beaty, Terri ; Casaburi, Richard ; Castaldi, Peter ; Cho, Michael H.; Comellas, Alejandro ; Crapo, James D.; Criner, Gerard ; Demeo, Dawn ; Christenson, Stephanie A.; Couper, David J.; Curtis, Jeffrey L.; Doerschuk, Claire M.; Freeman, Christine M.; Gouskova, Natalia A.; Han, Meilan K.; Hanania, Nicola A.; Hansel, Nadia N.; Hersh, Craig P.; Hoffman, Eric A.; Kaner, Robert J.; Kanner, Richard E.; Kleerup, Eric C.; Lutz, Sharon ; Martinez, Fernando J.; Meyers, Deborah A.; Peters, Stephen P.; Regan, Elizabeth A.; Rennard, Stephen I.; Scholand, Mary Beth; Silverman, Edwin K.; Woodruff, Prescott G.; O'Neal, Wanda K.; Bowler, Russell P. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2016 PLoS Genet 27532455
PMC4988780
19 MS008 SPIROMICS Protocol for Multicenter Quantitative Computed Tomography to Phenotype the Lungs. Sieren, Jered P.; Newell, John D.; Barr, Graham ; Bleecker, Eugene R.; Burnette, Nathan ; Carretta, Elizabeth E.; Couper, David ; Goldin, Jonathan ; Guo, Junfeng ; Han, Meilan K.; Hansel, Nadia N.; Kanner, Richard E.; Kazerooni, Ella A.; Martinez, Fernando J.; Rennard, Stephen ; Woodruff, Prescott G.; Hoffman, Eric A. Reading Center: Radiology (University of Iowa) 2016 Am J Respir Crit Care Med 27482984
PMC5074650
20 MS037 Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort. Putcha, Nirupama ; Barr, Graham ; Han, Meilan K.; Woodruff, Prescott G.; Bleecker, Eugene R.; Kanner, Richard E.; Martinez, Fernando J.; Smith, Benjamin M.; Tashkin, Donald P.; Bowler, Russell P.; Eisner, Mark D.; Rennard, Stephen I.; Wise, Robert A.; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2016 Thorax 26962015
PMC5235992
21 MS017 Design of a multi-center immunophenotyping analysis of peripheral blood, sputum and bronchoalveolar lavage fluid in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Freeman, Christine M.; Crudgington, Sean ; Stolberg, Valerie R.; Brown, Jeanette P.; Sonstein, Joanne ; Alexis, Neil E.; Doerschuk, Claire M.; Basta, Patricia V.; Carretta, Elizabeth E.; Couper, David J.; Hastie, Annette T.; Kaner, Robert J.; O'Neal, Wanda K.; Paine, Robert ; Rennard, Stephen I.; Shimbo, Daichi ; Woodruff, Prescott G.; Zeidler, Michelle ; Curtis, Jeffrey L. Clinical Center: Michigan (University of Michigan) 2015 J Transl Med 25622723
PMC4314767
22 MS013 Occupational exposures are associated with worse morbidity in patients with chronic obstructive pulmonary disease. Paulin, Laura M.; Diette, Gregory B.; Blanc, Paul D.; Putcha, Nirupama ; Eisner, Mark D.; Kanner, Richard E.; Belli, Andrew J.; Christenson, Stephanie ; Tashkin, Donald P.; Han, MeiLan ; Barr, Graham ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2015 Am J Respir Crit Care Med 25562375
PMC4384767
23 MS019 Parametric response mapping monitors temporal changes on lung CT scans in the subpopulations and intermediate outcome measures in COPD Study (SPIROMICS). Boes, Jennifer L.; Hoff, Benjamin A.; Bule, Maria ; Johnson, Timothy D.; Rehemtulla, Alnawaz ; Chamberlain, Ryan ; Hoffman, Eric A.; Kazerooni, Ella A.; Martinez, Fernando J.; Han, Meilan K.; Ross, Brian D.; Galbán, Craig J. Clinical Center: Michigan (University of Michigan) 2015 Acad Radiol 25442794
PMC4289437
24 MS010 A simplified score to quantify comorbidity in COPD. Putcha, Nirupama ; Puhan, Milo A.; Drummond, Bradley ; Han, Meilan K.; Regan, Elizabeth A.; Hanania, Nicola A.; Martinez, Carlos H.; Foreman, Marilyn ; Bhatt, Surya P.; Make, Barry ; Ramsdell, Joe ; DeMeo, Dawn L.; Barr, Graham ; Rennard, Stephen I.; Martinez, Fernando ; Silverman, Edwin K.; Crapo, James ; Wise, Robert A.; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2014 PLoS One 25514500
PMC4267736
25 MS005 Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study. O'Neal, Wanda K.; Anderson, Wayne ; Basta, Patricia V.; Carretta, Elizabeth E.; Doerschuk, Claire M.; Barr, Graham ; Bleecker, Eugene R.; Christenson, Stephanie A.; Curtis, Jeffrey L.; Han, Meilan K.; Hansel, Nadia N.; Kanner, Richard E.; Kleerup, Eric C.; Martinez, Fernando J.; Miller, Bruce E.; Peters, Stephen P.; Rennard, Stephen I.; Scholand, Mary Beth; Tal-Singer, Ruth ; Woodruff, Prescott G.; Couper, David J.; Davis, Sonia M. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2014 J Transl Med 24397870
PMC3928911
26 MS018 Comparison of spatially matched airways reveals thinner airway walls in COPD. The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study and the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). Smith, Benjamin M.; Hoffman, Eric A.; Rabinowitz, Dan ; Bleecker, Eugene ; Christenson, Stephanie ; Couper, David ; Donohue, Kathleen M.; Han, Meilan K.; Hansel, Nadia N.; Kanner, Richard E.; Kleerup, Eric ; Rennard, Stephen ; Barr, Graham Clinical Center: New York (Columbia University) 2014 Thorax 24928812
PMC4198462
27 MS002 Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). Couper, David ; LaVange, Lisa M.; Han, MeiLan ; Barr, Graham ; Bleecker, Eugene ; Hoffman, Eric A.; Kanner, Richard ; Kleerup, Eric ; Martinez, Fernando J.; Woodruff, Prescott G.; Rennard, Stephen Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2014 Thorax 24029743
PMC3954445
28 MS001 The COPD ontology and toward empowering clinical scientists as ontology engineers greenberg, jane ; O'Neal, Wanda ; Deshmukh, Rahul ; Lina, Huang ; Mostafa, Javed ; LaVange, Lisa M.; Carretta, Elizabeth E. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2010 Journal of Library Metadata
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